Sentinel node biopsy in desmoplastic thin melanoma: histogenetic reccomandations

Dunne et al have performed a full systematic literature review of sentinel lymph node biopsy (SLNB) in patients affected by desmoplastic melanoma (DM). Sixteen studies were included in the review and 1519 patients with SLNB were identified with nodal positivity in 99 cases (65%). Instead, the number of SLNB in desmoplastic thin melanoma (DTM) has been not reported. The authors believe that further research should be undertaken to establish if all patients with DTM should be offered SLNB based on stratification using clinico-pathological features (1).

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