Ventilation Defect Percent in Helium-3 MRI as a Biomarker of Severe Outcomes in Asthma

Publication date: Available online 10 November 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): David G. Mummy, Stanley J. Kruger, Wei Zha, Ronald L. Sorkness, Nizar N. Jarjour, Mark L. Schiebler, Loren C. Denlinger, Michael D. Evans, Sean B. Fain
Ventilation defect percent (VDP) measured in asthmatics with hyperpolarized helium-3 MRI was more strongly associated with ED visits and hospitalizations due to asthma exacerbation than were conventional biomarkers of lung function and inflammation.



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