Circulating allergen-specific Th2 lymphocytes: CCR4+ rather than CLA+ is the predominant phenotype in peanut allergic subjects

Publication date: Available online 8 December 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Lars H. Blom, Nanna Juel-Berg, Lau Fabricius Larsen, Kirsten S. Hansen, Lars K. Poulsen

Teaser

The skin and airway homing chemokine CCR4, but not CLA, emerged as the primary discriminating homing factor, of Th2 lymphocytes, suggesting that peanut sensitization occurs both via the skin and airways.


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