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Πέμπτη 7 Δεκεμβρίου 2017

Sample preparation for polar metabolites in bioanalysis

GA?id=C7AN01333G

Analyst, 2018, Advance Article
DOI: 10.1039/C7AN01333G, Minireview
Nicolas Drouin, Serge Rudaz, Julie Schappler
Sample preparation is a primary step of any bioanalytical workflow, especially in metabolomics where maximum information has to be obtained without spoiling the analytical instrument. The sample extraction of polar metabolites is still challenging but strategies exist to enable the phase transfer of hydrophilic metabolites from the biological phase to a clean interference-free phase.
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