Accuracy of FDG PET-CT response assessment following radiotherapy alone for head and neck squamous cell carcinoma: retrospective analysis of 45 patients

Abstract

FDG PET-CT is an established tool for response assessment following definitive concurrent chemoradiotherapy for head and neck squamous cell carcinoma with a high negative predictive value guiding treatment decisions.

Little data is available regarding the accuracy of FDG PET-CT for response assessment following definitive radiotherapy without chemotherapy.

We retrospectively analysed the accuracy of FDG PET-CT for response assessment following radiotherapy alone without planned neck dissection in 45 patients.

PET-CT had a high negative predictive value of 93% and positive predictive value of 88%.

Based upon the high negative predictive value, PET-CT can be used to avoid surgical intervention following radiotherapy alone

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