Αρχειοθήκη ιστολογίου

Σάββατο 17 Φεβρουαρίου 2018

Comorbidities of pyoderma gangrenosum: a retrospective multicentric analysis of 126 patients

Abstract

Pyoderma Grangrenosum (PG) is a rare neutrophilic dermatosis with challenging diagnosis and unclear underlying mechanisms. Multifactorial causes are purposed, including neutrophilic dysfunction, aberrant cellular immunity and cytokinic activities, and genetic predispositions1. An association with a systemic disease is classically described in 25 to 75% of cases, including inflammatory bowel diseases (IBD), inflammatory rheumatological diseases (IRD) and hematological disorders. Association of PG with cardiovascular disorders have also been proposed 2,3. Due to its rarity, the literature on PG-associated comorbidities remains limited to date.

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