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Τρίτη 27 Μαρτίου 2018

Occurrence, evolution, and functions of DNA phosphorothioate epigenetics in bacteria [Microbiology]

The chemical diversity of physiological DNA modifications has expanded with the identification of phosphorothioate (PT) modification in which the nonbridging oxygen in the sugar-phosphate backbone of DNA is replaced by sulfur. Together with DndFGH as cognate restriction enzymes, DNA PT modification, which is catalyzed by the DndABCDE proteins, functions as...

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