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Τρίτη 22 Μαΐου 2018

Codon usage of highly expressed genes affects proteome-wide translation efficiency [Systems Biology]

Although the genetic code is redundant, synonymous codons for the same amino acid are not used with equal frequencies in genomes, a phenomenon termed "codon usage bias." Previous studies have demonstrated that synonymous changes in a coding sequence can exert significant cis effects on the gene's expression level. However, whether...

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