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Τρίτη 15 Μαΐου 2018

FACT complex is required for DNA demethylation at heterochromatin during reproduction in Arabidopsis [Plant Biology]

The DEMETER (DME) DNA glycosylase catalyzes genome-wide DNA demethylation and is required for endosperm genomic imprinting and embryo viability. Targets of DME-mediated DNA demethylation reside in small, euchromatic, AT-rich transposons and at the boundaries of large transposons, but how DME interacts with these diverse chromatin states is unknown. The STRUCTURE...

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