Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems [Microbiology]

Riboswitches are noncoding portions of certain mRNAs that bind metabolite, coenzyme, signaling molecule, or inorganic ion ligands and regulate gene expression. Most known riboswitches sense derivatives of RNA monomers. This bias in ligand chemical composition is consistent with the hypothesis that widespread riboswitch classes first emerged during the RNA World,...

https://ift.tt/2sId5Cy