In vivo efficacy of ellagic acid against Candida albicans in a Drosophila melanogaster infection model [Pharmacology]

The aim of this study was to evaluate the antifungal activity and the toxicity of ellagic acid (EA) using a Drosophila melanogaster model. Candida albicans was inoculated in Toll heterozygous flies. Survival curves were obtained for the evaluation of the antimicrobial effect and toxicity of EA. A protective effect of Drosophila melanogaster from fungal infection was observed at non-toxic concentrations. This study showed that EA is promising for the treatment of candidiasis.

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