Antimalarial Lead-Optimization Studies on a 2,6-Imidazopyridine Series within a Constrained Chemical Space To Circumvent Atypical Dose-Response Curves against Multidrug Resistant Parasite Strains

Le Manach, C; Paquet, T; Wicht, K; Nchinda, AT; Brunschwig, C; Njoroge, M; Gibhard, L; ... Chibale, K; + view all Le Manach, C; Paquet, T; Wicht, K; Nchinda, AT; Brunschwig, C; Njoroge, M; Gibhard, L; Taylor, D; Lawrence, N; Wittlin, S; Eyermann, CJ; Basarab, GS; Duffy, J; Fish, PV; Street, LJ; Chibale, K; - view fewer (2018) Antimalarial Lead-Optimization Studies on a 2,6-Imidazopyridine Series within a Constrained Chemical Space To Circumvent Atypical Dose-Response Curves against Multidrug Resistant Parasite Strains. Journal of Medicinal Chemistry , 61 (20) pp. 9371-9385. 10.1021/acs.jmedchem.8b01333 .

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