Αρχειοθήκη ιστολογίου

Τρίτη 20 Νοεμβρίου 2018

Criticality in tumor evolution and clinical outcome [Genetics]

How mutation and selection determine the fitness landscape of tumors and hence clinical outcome is an open fundamental question in cancer biology, crucial for the assessment of therapeutic strategies and resistance to treatment. Here we explore the mutation-selection phase diagram of 6,721 tumors representing 23 cancer types by quantifying the...

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