Head & NeckReview of emerging biomarkers in head and neck squamous cell carcinoma in the era of immunotherapy and targeted therapyAbstract Background Biomarkers in head and neck squamous cell carcinoma (HNSCC) emerge rapidly in recent years, especially for new targeted therapies and immunotherapies. Methods Recent, relevant peer‐reviewed evidence were critically reviewed and summarized. Results This review article briefly introduces essential biomarker concepts, including purposes and classifications...
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ScienceDirect Publication: Pathology - Research and PracticeHobnail cells in encapsulated papillary thyroid carcinoma: Report of 2 cases with immunohistochemical and molecular findings and literature analysisPublication date: Available online 30 September 2019Source: Pathology - Research and PracticeAuthor(s): Shweta Agarwal, Qandeel Sadiq, Ibrahim OrtancaAbstractPapillary thyroid carcinoma (PTC) is the most common malignant tumor of the thyroid gland with most tumors behaving in an indolent fashion....
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CancerCM-Path Molecular Diagnostics Forum—consensus statement on the development and implementation of molecular diagnostic tests in the United KingdomBritish Journal of Cancer, Published online: 02 October 2019; doi:10.1038/s41416-019-0588-1CM-Path Molecular Diagnostics Forum—consensus statement on the development and implementation of molecular diagnostic tests in the United KingdomCancerTue Oct 01, 2019 17:00CM-Path Molecular Diagnostics Forum—consensus statement on the development and implementation...
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Radiotherapy and OncologyEnd-to-end empirical validation of dose accumulation in MRI-guided adaptive radiotherapy for prostate cancer using an anthropomorphic deformable pelvis phantomIn-room image-guidance has become a cornerstone in radiotherapy, both for assessing inter-fractional anatomical changes and performing adaptive radiotherapy (ART) [1,2]. The position and shape of target and critical organs may vary during the course of radiotherapy and, in the absence of online plan adaptation, can...
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Annals of Oncology - current issue,1680PA global patient-driven Facebook study in a very rare sarcoma: Health-related quality of life in epithelioid hemangioendothelioma (EHE) patientsAbstractBackgroundEHE is a vascular sarcoma with an incidence of ≤ 1 per 1 million/year, and an unpredictable clinical course with significant symptom burden. Recruiting EHE patients for studies is difficult and health-related quality of life (HRQoL) in these patients is unknown. We aimed to study the impact of EHE...
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OtorhinolaryngologyCyst of the right lymphatic ductPublication date: Available online 30 September 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): I. Stárek, R. Salzman, Z. Pokorná, D. SkanderováAbstractIntroductionCysts originating from cervical lymphatic ducts are very rare affections. However, they play an important role in the differential diagnosis of supraclavicular masses. The aetiology remains unclear. Practically all cases arise from the thoracic ductOtorhinolaryngologyTue...
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Alcohol and HomeostasisOsmolyte accumulation regulates the SUMOylation and inclusion dynamics of the prionogenic Cyc8-Tup1 transcription corepressor.Related ArticlesOsmolyte accumulation regulates the SUMOylation and inclusion dynamics of the prionogenic Cyc8-Tup1 transcription corepressor. PLoS Genet. 2019 04;15(4):e1008115 Authors: Nadel CM, Mackie TD, Gardner RG Abstract Environmental stressors can severely perturb cellular homeostasis and compromise viability. To cope with environmental stressors,...
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Severe Acute Kidney Injury Due to Nivolumab/Ipilimumab-induced Granulomatosis and Fibrinoid Vascular Necrosis.Severe Acute Kidney Injury Due to Nivolumab/Ipilimumab-induced Granulomatosis and Fibrinoid Vascular Necrosis. J Immunother. 2019 Sep 24;: Authors: Person F, Chahoud-Schriefer T, Fehrle W, Janneck M, Huber TB, Wiech T Abstract Immune-checkpoint inhibitors have revolutionized the treatment of cancers in recent years. Four drugs have obtained FDA approval in a variety of cancer types. Immune-related...
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Nanomaterials, Vol. 9, Pages 1403: Facile Synthesis of GNPs@NixSy@MoS2 Composites with Hierarchical Structures for Microwave AbsorptionNanomaterials, Vol. 9, Pages 1403: Facile Synthesis of GNPs@NixSy@MoS2 Composites with Hierarchical Structures for Microwave Absorption Nanomaterials doi: 10.3390/nano9101403 Authors: Wenfeng Zhu Li Zhang Weidong Zhang Fan Zhang Zhao Li Qing Zhu Shuhua Qi Graphene-based powder absorbers have been used to attain excellent microwave absorption. However, it is not clear...
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Journal of Clinical MedicineJCM, Vol. 8, Pages 1581: Photodynamic Therapy: A Brief HistoryJCM, Vol. 8, Pages 1581: Photodynamic Therapy: A Brief History Journal of Clinical Medicine doi: 10.3390/jcm8101581 Authors: David Kessel Photodynamic therapy (PDT) involves the selective sensitization of tissues to light. A major advance in the field occurred when Thomas Dougherty at the Roswell Park Cancer Institute initiated a series of clinical studies that eventually led to FDA approval of the procedure....
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Geriatrics, Vol. 4, Pages 55: Comparing Inpatient Complication Rates between Octogenarians and Nonagenarians Following Primary and Revision Total Hip Arthroplasty in a Nationally Representative Sample 2010–2014Geriatrics, Vol. 4, Pages 55: Comparing Inpatient Complication Rates between Octogenarians and Nonagenarians Following Primary and Revision Total Hip Arthroplasty in a Nationally Representative Sample 2010–2014 Geriatrics doi: 10.3390/geriatrics4040055 Authors: Dugdale Tybor Kain Smith We compared...
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Cancers, Vol. 11, Pages 1480: Epigenetic Mechanisms of Escape from BRAF Oncogene DependencyCancers, Vol. 11, Pages 1480: Epigenetic Mechanisms of Escape from BRAF Oncogene Dependency Cancers doi: 10.3390/cancers11101480 Authors: Khaliq Fallahi-Sichani About eight percent of all human tumors (including 50% of melanomas) carry gain-of-function mutations in the BRAF oncogene. Mutated BRAF and subsequent hyperactivation of the MAPK signaling pathway has motivated the use of MAPK-targeted therapies for...
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Antibiotics, Vol. 8, Pages 173: Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-AnalysisAntibiotics, Vol. 8, Pages 173: Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-Analysis Antibiotics doi: 10.3390/antibiotics8040173 Authors: Chiu Sarwal Feinstein Hennessey Background: Oral vancomycin is a first line treatment for an...
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Chronic Refractory Cough: Objective Improvement With Aerodynamic-FocusedPrevious investigations have reported that a chronic cough that is refractory to medical therapies improves with behavioral therapies. However, the treatment parameters that may account for improvement in cough symptoms have not yet been objectively documented. The purpose of this study was to document changes in chronic refractory cough using a breath training protocol.Acoustic Voice Quality Index as a Potential Tool for Voice...
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Eosinophilic esophagitis after total gastrectomy treated with proton pump inhibitors: a case reportAbstractEosinophilic esophagitis (EoE) is a chronic, immune-mediated disorder in the esophagus characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation. EoE and Gastro Esophageal Reflux Disease (GERD) are known not to be mutually exclusive and share a complex relationship. Proton pump inhibitors (PPIs), which are generally used in the treatment of GERD, could...
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Philosophical Transactions of the Royal Society ATheme issue 'Topological and geometrical aspects of mass and vortex dynamics' compiled and edited by Stefanella Boatto and David G. DritschelVol. 377, No. 2158, (November 2019) The above issue is now available online at:https://royalsocietypublishing.org/toc/rsta/2019/377/2158?ai=aqlb&ui=cbwb&af=HClick the links below to view the abstract for each article, or click the link above to view all Just Released articles for this journal.PREFACEPreface:...
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Geriatrics' turning pointThe Summer Book: perspectives on communication and connectingDeveloping a Frailty Index from routinely collected data in the Emergency Department among of hospitalized patientsKey summary pointsAimTo develop a Frailty Index from data routinely collected during the standard clinical assessment in the Emergency Department and to test its predictive capacity for adverse outcomes.FindingsThe Frailty Index presented in this study is significantly correlated with age and associated...
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Audit of the quality of intraoral periapical radiograph: An institutional studySunita Shankarrao Patankar, Freny R Karjodkar, Kaustubh P Sansare, Shalvi VoraJournal of Oral and Maxillofacial Radiology 2019 7(2):21-24Objectives: To reduce the radiation exposure to patients, to improve the diagnostic proficiency of radiographs, and to collect data which will help decide the action of improvement in performance. Materials and Methods: The audit consisted of two cycles: Audit Cycle 1 analyzed randomly...
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Insertion Mutations of the s haggy Gene, Encoding Protein Kinase GSK3, Extend Drosophila melanogaster LifespanAbstractThe shaggy gene of Drosophila melanogaster encodes highly conserved serine-threonine protein kinase GSK3 (Glycogen Syntase Kinase 3), which plays an important role in different signaling pathways and metabolic processes. This study is the first to demonstrate that shaggy mutations affect lifespan, with an increase in longevity associated with a decrease in synapse activity. The results...
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Correlations between sedimentation sign, dural sac cross-sectional area, and clinical symptoms of degenerative lumbar spinal stenosis" by Sangbong Ko (Eur Spine J [2018] 27:1623–1628)Correction to: Surgical growth guidance with non-fused anchoring segments in early-onset scoliosisThe preoperative X-ray presented in Figure 1 of the original publication erroneously was not the latest radiographic image taken before the index surgery at the age of 3 years.Letter to the Editor concerning "Indirect foraminal...
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Connection between polymorphisms in HTR2A , TPH2 , BDNF , TOMM40 genes and the successful mastering of human–computer interfacesAbstractThe development of human–computer interfaces in different individuals occur with different efficiencies, this is due to the individual characteristics of the genotype determined by the single-nucleotide polymorphism (SNP) of a person. Here, we checked the connection between the success of the acquisition of the brain-computer, eye-tracking, electromyographic, and...
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A diabetic patient in whom Hb Weesp was incidentally detected when her HbA1c level was measuredAbstractThe level of glycated hemoglobin A1c (HbA1c) is widely used to monitor long-term glycemic control in patients with diabetes mellitus. There are more than 30 methods for measuring HbA1c levels. In recent times, high-performance liquid chromatography (HPLC) has become the most commonly used method in Japan. However, HPLC-based HbA1c level measurements do not accurately reflect glycemic control in...
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The American Academy of Pediatrics,Pediatric Application of Coding and Valuation SystemsDavid M. Kanter, Richard Lander, Richard A. Molteni and COMMITTEE ON CODING AND NOMENCLATURE, PRIVATE PAYER ADVOCACY ADVISORY COMMITTEEPediatric Application of Coding and Valuation SystemsDavid M. Kanter, Richard A. Molteni and COMMITTEE ON CODING AND NOMENCLATURERecommendations for Prevention and Control of Influenza in Children, 2019–2020COMMITTEE ON INFECTIOUS DISEASESExecutive Summary: Criteria for Critical...
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Pediatrics , October 2019, VOLUME 144 / ISSUE 4 Articles Food Insecurity, Health, and Development...
Pediatrics ,October 2019, VOLUME 144 / ISSUE 4ArticlesFood Insecurity, Health, and Development in Children Under Age Four YearsChloe R. Drennen, Sharon M. Coleman, Stephanie Ettinger de Cuba, Deborah A. Frank, Mariana Chilton, John T. Cook, Diana B. Cutts, Timothy Heeren, Patrick H. Casey and Maureen M. BlackFood Insecurity and Health Care UseAlon Peltz and Arvin GargFood Insecurity and Child HealthMargaret M.C. Thomas, Daniel P. Miller and Taryn W. MorrisseyPrevalence and Trends of Developmental...
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The LaryngoscopeVolume 129, Issue 10Pages: i-vii, 2205-2441, E342-E376October 2019Issue InformationMastheadPages: i-ii | First Published: 30 September 2019Table of contentsPages: iii-vii | First Published: 30 September 2019EditorialNinth editor‐in‐chief of the laryngoscopeSamuel H. Selesnick MD, FACS, Editor‐in‐ChiefPages: 2205 | First Published: 20 August 2019Triological Society Best PracticeOtology/NeurotologyAre diuretics useful in the treatment of meniere disease?Sagit Stern Shavit MD, Anil K....
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Advanced Biomedical Research ( Adv Biomed Res)Surprisingly, the Result of an Unplanned Pregnancy after Cranial Radiotherapy: A Case Report (Successful Childbirth after Brain Astrocytoma)Azar Danesh Shahraki, Leila Mousavi, Amirreza Farhadian DehkordiAdv Biomed Res 2019, 8:54 (23 September 2019)[ABSTRACT] [HTML FULL TEXT] [PDF] [Mobile HTML Full text ] [EPub]Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes...
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A Rare Case of Spontaneous Bilateral Ruptured Tubal Ectopic PregnancyAbstractBilateral tubal ectopic pregnancy is very rare, spontaneous cases being exceptional. Here, the authors report a case of spontaneous bilateral tubal ectopic pregnancy of 10-weeks gestation diagnosed and managed at Bharatratna Dr. Babasaheb Ambedkar Municipal and General Hospital, Kandivali, Mumbai. A 29-year-old, G2P1L1 patient presented in the emergency department with 3-months amenorrhea, abdominal pain and vaginal bleeding....
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Journal of Surgical OncologyEarly ViewOnline Version of Record before inclusion in an issueRESEARCH ARTICLESDevelopment and validation of a risk stratification model for immediate microvascular breast reconstructionMélissa Roy MDCM, MSc, Stephanie Sebastiampillai HBSc, Siba Haykal MD, PhD, Toni Zhong MD, MHS, Stefan O. P. Hofer MD, PhD, Anne C. O'Neill MBBCh, PhDVersion of Record online: 28 September 2019RESEARCH ARTICLESThe effect of radical cystectomy on survival in patients with metastatic urothelial...
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Botulinum toxin type D blocks autonomic cholinergic synapses in humans: discussion of a potential therapeutic useAbstractBased on epidemiological data it was believed that botulinumtoxin type D (BT-D) may not block human cholinergic synapses. We wanted to investigate BT-D's effect on the autonomic cholinergic synapse in humans. For this, we compared in four volunteers intraindividually the hypohidrotic effect of intradermal BT-D and BT-A in Minor's iodine starch sweat test. Altogether, we studied...
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"Association of Early Systemic Corticosteroid Therapy with Mortality in Patients with Stevens–Johnson Syndrome or Toxic Epidermal Necrolysis: A Retrospective Cohort Study Using a Nationwide Claims Database"Comment on: "Association of Early Systemic Corticosteroid Therapy with Mortality in Patients with Stevens–Johnson Syndrome or Toxic Epidermal Necrolysis: A Retrospective Cohort Study Using a Nationwide Claims Database"Comment on: Vascular Tests for DermatologistsAuthors' Reply to Laneelle et al.:...
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Differentialdiagnose in der AugenheilkundeSpontaneous self-resolution of vitreomacular diseases: a three-case reportSummaryBackgroundIn many cases, macular hole and epiretinal membrane require surgical therapy. In rare cases, spontaneous resolution is possible.Patients and methodsThree cases of vitreoretinal diseases are presented: one case of spontaneous closure of an idiopathic stage III macular hole and two cases of spontaneous self-resolution of an epiretinal membrane.ResultsThe idiopathic stage III...
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Papulosis bowenoide linealPublication date: Available online 25 September 2019Source: Actas Dermo-SifiliográficasAuthor(s): F. Allegue, C. Fachal, D. González-Vilas, A. ZulaicaPlacas similares a xantomas como forma de presentación de una histiocitosis de células de Langerhans en un paciente en edad adultaPublication date: Available online 14 September 2019Source: Actas Dermo-SifiliográficasAuthor(s): E. Boyuk, I. Bulur, F. Canaz, O. CilingirNódulo en la mama tras radioterapiaPublication date: Available...
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REM sleep may help the brain forget,Scientists identified neurons in mice that are involved in actively forgetting memories during dream sleep.How cancer vesicles breach the blood-brain barrierSmall particles from cancer cells called extracellular vesicles cross the blood-brain barrier to make the brain more hospitable to metastatic tumors.Disrupting host protein blocks enterovirus infections in miceResearchers found a host protein that enteroviruses, which cause many cases of the common cold as...
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NIH researchers develop MRI with lower magnetic field for cardiac and lung imaging10/01/2019 10:00 AM EDTRedesigned MRI holds promise for the diagnosis and treatment of diseases.2019 NIH Director's awards for High-Risk, High-Reward Research Program Announced10/01/2019 10:00 AM EDTNinety-three awards will fund highly innovative, high-impact biomedical research.Emerging parasitic disease mimics the symptoms of visceral leishmaniasis in people10/01/2019 10:30 AM EDTThe parasite, however, does not respond...
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Increasing value of autopsies in patients with brain tumors in the molecular eraAbstractBackgroundPediatric brain tumors are associated with high morbidity and mortality, in part due to insufficient understanding of tumor biology. With limited tissue allocation for research from surgical specimens, a key barrier to improving biological understanding, brain tumor autopsies have become an increasingly valuable resource. This study reviews the brain tumor autopsy practice at our institution and describes...
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Cancer Research October 2019; 79 (19)Breaking InsightsHighlights from Recent Cancer LiteratureReviewAuthorChoice Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-OncologyXuanmao Jiao et al.Cancer Research HighlightsA Breath of Fresh Air: Opening up the Lung Cancer GenomeAnne M. BowcockSequencing the Events That Mediate Progression of Premalignant Lung LesionsDaniel T. MerrickGenome and EpigenomePathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic...
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Bit1-a novel regulator of astrocyte function during retinal development: proliferation, migration, and paracrine effects on vascular endothelial cellAbstractStudies have shown that astrocyte plays an important role in the formation of retinal vasculature during development. For our study, we investigated the role of Bcl2 inhibitor of transcription 1 (Bit1) in regulating astrocyte function from developing retina and its paracrine effects on vascular endothelial cell. Expression pattern of Bit1 was...
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Sympathetic Blocks for Complex Regional Pain Syndrome, In patients with complex regional pain syndrome, skin temperature change is not associated with sympathetic block pain reduction. The short- and long-term effects of sympathetic blocks are not associated with spinal cord situation outcomes. Intestinal Ischemia-Reperfusion Injury and HistonesIn male mice, recombinant thrombomodulin administration after intestinal ischemia-reperfusion increased survival rate. Histones...
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premium Bruker's New Biotyper Opens Up Lipid Analysis, Antibiotic Resistance TestingPublished on Sep 26, 2019 NSIGHT2 Trial Finds Whole-Genome Sequencing Has High Analytical PerformancePublished on Sep 26, 2019De Novo Genome Assembly for Large, Complex GenomesThis application note from Illumina discusses how the NovaSeq 6000 sequencer with NRGene's DeNovoMAGIC bioinformatics system produces de novo assemblies for large, complex crop genomes of exceptional quality.Download it from GenomeWeb's White...
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Retraction Note: Three-year Experience with Alendronate Treatment in Postmenopausal Osteoporotic Japanese Women with or without Renal Dysfunction: A Retrospective StudyThe Editor has retracted this article [Iwamoto J, Sato Y, Uzawa M, Takeda T, Matsumoto H. Three-year Experience with Alendronate Treatment in Postmenopausal Osteoporotic Japanese Women with or without Renal Dysfunction: A Retrospective Study. Drugs Aging 2012; 29(2): 133-142.]. After publication, serious concerns were raised with respect...
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Hypoxia Regulated Gene Network in Glioblastoma Has Special Algebraic Topology Structures and Revealed Communications Involving Warburg Effect and Immune RegulationAbstractHypoxia regulated genes (HRGs) formed a complex molecular interaction network (MINW), contributing to many aspects of glioblastoma (GBM) tumor biology. However, little is known about the intrinsic structures of the HRGs–MINW, mainly due to a lack of analysis tools to decipher MINWs. By introducing general hyper-geometric distribution,...
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Total abdominal proctocolectomy: what is new with the da Vinci Xi?Ultrasound optic nerve sheath diameter evaluation in patients undergoing robot-assisted laparoscopic pelvic surgeryAbstractFollowing the interesting reading of the article "A randomised trial to compare the increase in intracranial pressure as correlated with the optic nerve sheath diameter during propofol versus sevoflurane-maintained anesthesia in robot-assisted laparoscopic pelvic surgery", the authors comment some aspects about...
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Large-Eddy Simulations of the Steady Wintertime Antarctic Boundary LayerAbstractObservations of two typical contrasting weakly stable and very stable boundary layers from the winter at Dome C station, Antarctica, are used as a benchmark for two centimetre-scale-resolution large-eddy simulations. By taking the Antarctic winter, the effects of the diurnal cycle are eliminated, enabling the study of the long-lived steady stable boundary layer. With its homogeneous, flat snow surface, and extreme stabilities,...
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A case of allograft ureteral stone successfully treated with antegrade ureteroscopic lithotripsy: use of a 3D-printed model to determine the ideal approachAbstractWe present the case of a 46-year-old man who underwent successful antegrade ureteroscopy for lithiasis in his allograft ureter. At a scheduled follow-up 15 years after transplantation, computed tomography (CT) detected a 12-mm renal stone in the renal pelvis of the transplanted kidney. During his follow-up, gross hematuria was seen; the...
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Several issues on the article: patient-reported quality of life and pain after permissive weight bearing in surgically treated trauma patients with tibial plateau fractures: a retrospective cohort studyAnalysis of complication after open coracoid transfer as a revision surgery for failed soft tissue stabilization in recurrent anterior shoulder instabilityAbstractBackgroundThe coracoid transfer represents a treatment option for patients with recurrent shoulder instability. Only a few studies exist...
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Reasons You May Have Brain FogPhoto of man with brain fog1 / 10What Is It?"Brain fog" isn't a medical condition. It's a term used for certain symptoms that can affect your ability to think. You may feel confused or disorganized or find it hard to focus or put your thoughts into words.Swipe to advancePhoto of pregnant woman using computer2 / 10PregnancyMany women find it's harder to remember things during pregnancy. Carrying a baby can change your body in lots of ways, and chemicals released to protect...
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Supplements You Shouldn't Try"Natural" means they're fine, right? Guess again. These supplements may not be safe, especially if you have certain medical conditions or take some medications.Read More Supplements in hand1 / 15Supplement SafetyIt seems like these products should be harmless. After all, you use herbs all the time when you're cooking. But some may not be safe, especially if you have certain medical conditions or take some medications. Talk with your doctor before taking any supplements.Swipe...
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Prescription Thyroid Replacement Does Not Affect Outcomes in an Intensive Weight Reduction ProgramWith the complex role of the thyroid in metabolism and conflicting evidence of weight gain or loss as a result of prescription thyroid hormone replacement (THR), it is important to understand how THR affects weight loss beyond the standard measures of body weight % and body mass index (BMI). We examined differences in body composition improvement in individuals taking and not taking THR over 60 d of...
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Dissociating neural correlates of retrieval practice and elaborative study in associative recognition memoryRetrieval practice effect refers to better long-term retention enhanced by active retrieval compared to re-studying, which has been widely demonstrated. However, controversies remain as to whether the underlying mechanism of this effect could be attributed to semantic elaboration. We investigated whether retrieval practice and elaboration were equivalent by observing the underlying cognitive...
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Are Epidural Steroid Injections Beneficial for Patients With Degenerative Lumbar Spondylolisthesis?No abstract availableOdontoid Fractures: A Critical Review of Current Management and Future DirectionsOdontoid fractures represent one of the most common and controversial injury types affecting the cervical spine, being associated with a high incidence of nonunion, morbidity, and mortality. These complications are especially common and important in elderly patients, for which ideal treatment options...
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Papilledema, Demyelinating Optic Neuritis and its Subtypes Ischemic Optic Neuropathies: Diagnosis...
Papilledema,Demyelinating Optic Neuritis and its SubtypesIschemic Optic Neuropathies: Diagnosis and ManagementChiasmal and Retrochiasmal DisordersTransient Visual LossA Review of Third Nerve PalsiesThyroid Eye Disease and Myasthenia GravisAnisocoriaNonorganic Visual DisordersNo abstract available
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Novel potential biomarkers for the diagnosis and monitoring of patients with ulcerative colitisUnambiguously, great progress has been achieved in the unraveling of more pathological pathways implicated in the development and progression of ulcerative colitis during the last decades. Novel effective drugs that have augmented the management armamentarium have been developed alongside this growing comprehension of the disease, rendering mucosal healing not only a feasible but the optimal goal of every...
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A systematic review of questionnaires on itch by the Special Interest Group "Questionnaires" of the International Forum for the Study of Itch (IFSI)Introduction: Itch can be perceived differently across patients and it can affect daily life in various ways. It is essential to assess those aspects that are relevant for the individual patient's needs to improve treatment of patients suffering from acute or chronic itch. The International Forum for the Study on Itch (IFSI) Special Interest Group on...
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Photochemistry and PhotobiologyAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.Research ArticlesA Dual Emissive Coumarin–urea Derivative with an Electron‐withdrawing Substituent in the Presence of Acetate AnionTomoyuki Shinoda, Yoshinobu Nishimura, Tatsuo AraiFirst Published: 27 September 2019RESEARCH ARTICLESATR Kinase Activity Limits Mutagenesis and Promotes the Clonogenic Survival of Quiescent Human...
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Pakistan Journal of Biological Sciences - Simultaneous Administration of Boesenbergia pandurata Extract and Vaccination to Stimulate Immune Response in Tilapia, Oreochromis niloticusPosted:Background and Objective: The use of adjuvants or immunostimulants is often necessary to increase vaccine efficacy, in this study we evaluated the improvement of the immune response in tilapia treated by either oral and immersion administration with vaccine and Boesenbergia pandurata extract (BPE). Materials and...
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Audio Summary: Effect of Vitamin C in Sepsis, Anesthesia vs Sedation for Stroke Thrombectomy, CKD...
Audio Summary: Effect of Vitamin C in Sepsis, Anesthesia vs Sedation for Stroke Thrombectomy, CKD Review, and moreORIGINAL INVESTIGATIONAssociation of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and ObesityAli Aminian, MD; Alexander Zajichek, MS; David E. Arterburn, MD, MPH; et al.Earn CME creditClinical Review Audio: Bariatric Surgery and Cardiovascular Outcomes in Patients With Type 2 Diabetes and ObesityEditorial: The Role of Bariatric Surgery...
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Skin Research and TechnologyEarly ViewOnline Version of Record before inclusion in an issueORIGINAL ARTICLESComparative study into facial sebum level, pore size, and skin hydration between oily‐skinned and dry‐skinned Thai womenKunlawat Thadanipon, Jutarat KitsongsermthonVersion of Record online: 28 September 2019 Open AccessORIGINAL ARTICLES3D surface texture analysis of high‐resolution normal fields for facial skin condition assessmentAlassane Seck, Hannah Dee, William Smith, Bernard TiddemanVersion...
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AIRWAY & RESPIRATORY, EXCLUSIVES, PATIENT CARE, TRAINING,Pediatric BIPAP,By Jake Weinstein, DNP, ACNP, Paramedic and Judson Smith, MHA, Paramedic | 9.19.19ObjectivesUnderstand specific challenges of pediatric airway management in EMSReview the limits of NIPPV therapyExplain indications and contraindications for BIPAP/CPAP in pediatricsAnalyze specific cases for application of NIPPV in EMSIntroductionDeployment of CPAP and BIPAP in EMS has evolved over the last decade and is arguably first line...
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An oropharyngeal airway is the first airway device that all levels of EMS providers are taught to use. As we advance in our airway skills, "insert an oropharyngeal airway" eventually becomes a simple line on a testing sheet. However, the oropharyngeal airway (OPA) has a rich history that many providers are never taught. Although many people focus on advanced airways and their ever-evolving designs, let's take a few minutes and look at this time-tested basic airway.The first OPA was made of metal...
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EMS AIRWAYInsert an Oropharyngeal AirwayAlthough many people focus on advanced airways and their ever-evolving designs, let's take a few minutes and look at this time-tested basic airway.READ MORE
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Human homeostasisHigh-density genome-wide associat...Clinical Anatomy"It is the novel province of anato...Gait & PostureEffects of plantar intrinsic foot mu...BioMed Research InternationalCalcium Fluxes in Wor...Head and NeckEfficacy of buffered local anaestheti...Clinical and translational oncologyComment on "Pro...Journal of Internal MedicineIssue InformationJourn...Hellenic Anticancer Institute , Concomitant Treatm...Journal of Evolutionary BiologyGreater opportuniti...Journal of VoiceAcoustic...
Tue Oct 01, 2019 09:11
Clinical Anatomy "It is the novel province of anatomy to tell the truth, the whole truth, and nothing...Clinical Anatomy"It is the novel province of anatomy to tell the truth, the whole truth, and nothing but the truth…"Clinical AnatomyMon Sep 30, 2019 08:51Latest Results for Journal of the History of BiologyThe Creativity of Natural Selection? Part II: The Synthesis and SinceAbstract This is the second of a two-part essay on the history of debates concerning the creativity of natural selection,...
Tue Oct 01, 2019 09:05
Foraging consistency of coral reef fishes across e...Nanomaterials, Vol. 9, Pages 1396: Enhanced Breakd...Journal of Clinical MedicineJCM, Vol. 8, Pages 156...International Journal of Environmental Research an...Antibiotics, Vol. 8, Pages 171: Phenylboronic Acid...Incidence and Outcomes of Sepsis in Korea: A Natio...Mucinous cystadenoma of oral minor salivary glands...Follow-Up of an Implant-Supported Rehabilitation A...Ebola virus disease: Recent advancs in diagnostics...Social determinants of mental...
Tue Oct 01, 2019 08:32
International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 3712: UK Postal Delivery Workers' Occupational Sun Safety: Using Behavior Change Theories to Identify Intervention PathwaysIJERPH, Vol. 16, Pages 3712: UK Postal Delivery Workers' Occupational Sun Safety: Using Behavior Change Theories to Identify Intervention Pathways International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193712 Authors: Jonathan Houdmont Raymond Randall Alistair...
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Quality evaluation of no-reference MR images using multidirectional filters and image statistics....
Quality evaluation of no-reference MR images using multidirectional filters and image statistics.Related ArticlesQuality evaluation of no-reference MR images using multidirectional filters and image statistics. Magn Reson Med. 2018 09;80(3):914-924 Authors: Jang J, Bang K, Jang H, Hwang D, Alzheimer's Disease Neuroimaging Initiative PMID: 29383737 [PubMed - indexed for MEDLINE]pubmed: misdiagnosis of alzh...Tue Oct 01, 2019 03:08SAGE Publications Inc: Technology in Cancer Research & Treatment:...
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Systematic review and meta-analysis of carbapenem-resistance of Acinetobacter baumannii in Iran.Systematic review and meta-analysis of carbapenem-resistance of Acinetobacter baumannii in Iran. Infect Disord Drug Targets. 2019 Sep 29;: Authors: Shakib P, Choolandaimy ZB, Rezaie F, Bahmani M, Delfani S Abstract INTRODUCTION: The prevalence of carbapenem resistance in Acinetobacter baumannii (A. baumannii) has been increased in worldwide. Thus therapeutic options are extremely limited. We performeInfectious...
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Significance of the Marginal Mandibular Branch in Relation to Facial Palsy Reconstruction: Assessment of Microanatomy and Macroanatomy Including Axonal Load in 96 Facial Halves.Significance of the Marginal Mandibular Branch in Relation to Facial Palsy Reconstruction: Assessment of Microanatomy and Macroanatomy Including Axonal Load in 96 Facial Halves. Ann Plast Surg. 2019 Sep 16;: Authors: Mandlik V, Ruewe M, Engelmann S, Geis S, Taeger C, Kehrer M, Tamm ER, Bleys R, Prantl L, Kehrer A Abstract...
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Eosinophilic Pneumonia Putatively Induced by Vancomycin: A Case Report.Related ArticlesEosinophilic Pneumonia Putatively Induced by Vancomycin: A Case Report. Am J Case Rep. 2019 Sep 30;20:1440-1445 Authors: Isono T, Sawaguchi H, Kusumoto H, Shiono H Abstract BACKGROUND Herein, we describe a case of eosinophilic pneumonia that was likely to have been induced by vancomycin. CASE REPORT A 65-year-old man on maintenance hemodialysis presented with chest pain and dyspnea. Hpubmed: "am j case rep"[jour...Tue...
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Cathepsin L secretion by host and neoplastic cells potentiates invasion.Related ArticlesCathepsin L secretion by host and neoplastic cells potentiates invasion. Oncotarget. 2019 Sep 17;10(53):5560-5568 Authors: Dykes SS, Fasanya HO, Siemann DW Abstract The presence of macrophages within breast tumors correlates with metastatic potential. These tumor-associated macrophages often take on a pro-tumorigenic (M2-like) phenotype resulting in the secretion of growth factors andOncotarget,Albany, N.Y. :...
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Dysphagia - RehabilitationRehabilitation of persistent aphagia after Wallenberg syndrome by a novel combination method.Related ArticlesRehabilitation of persistent aphagia after Wallenberg syndrome by a novel combination method. Iran J Neurol. 2019 Apr 04;18(2):90-92 Authors: Sariaslani P, Parsa D, Mohammadi H PMID: 31565208 [PubMed]Dysphagia - RehabilitationTue Oct 01, 2019 03:44A specific protocol of myo-functional therapy in children with Down syndrome. A pilot study.Related ArticlesA specific...
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Journal of Medical Imaging and Radiation OncologyAdrenal collision tumour comprised of adrenocortical carcinoma and myelolipoma in a patient with congenital adrenal hyperplasiaSummary Adrenal myelolipoma is a benign tumour characterized by the presence of macroscopic fat. Further workup is not necessary if a diagnosis of adrenal myelolipoma is obtained via imaging. We report the first case of adrenal collision tumour comprised of adrenocortical carcinoma and myelolipoma in a patient with bilateral...
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Oral BiologyCalcium promotes differentiation in ameloblast-like LS8 cells by downregulation of phosphoinositide phosphatidylinositol 3 kinase /protein kinase B pathwayPublication date: Available online 30 September 2019Source: Archives of Oral BiologyAuthor(s): Gao Jianghong, Gao Zhen, Dang Fan, Li Xinmei, liu Hao, Liu Xiaojing, Gao Meili, Ruan JianpingAbstractObjectivesTo investigate the effect and mechanism of calcium on LS8 cell differentiation, especially on phosphoinositide phosphatidylinositol...
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Plastic, Reconstructive & Aesthetic Surgery Can Plastic Surgeons Really Tell What Type of Implant...
Plastic, Reconstructive & Aesthetic SurgeryCan Plastic Surgeons Really Tell What Type of Implant a Patient Is Wearing?Breast augmentation is the second most commonly performed aesthetic surgery in the United States and the use of different implant materials has changed over the years. Aesthetic goals and results in implant-based breast surgery vary widely based on age, geography, and surgeon preference.1 Most surgeons have emphatically returned to silicone implants once the moratorium on them...
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MycosesAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.ORIGINAL ARTICLESThe clinical and microbiological features and outcomes of fungal keratitis over 9 years in Sydney, AustraliaStephanie L Watson, Maria Cabrera‐Aguas, Lisa Keay, Pauline Khoo, Dominic McCall, Monica M LahraFirst Published: 26 September 2019ORIGINAL ARTICLESMalassezia colonization on a reconstructed human epidermis: imaging studiesA...
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Software for warranty optimizationAbstractThe research article is associated with warranty optimization. Warranty is one of the most important factors for each organization because it accounts for a large profit in the organizations. In the past research articles, the models developed are only for specific problems of warranty optimization. In this research, a generic model is developed that can be applied to any system for calculating the optimal alternatives, optimal types of warranty policy and...
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Bullous Diseases in Children: A Review of Clinical Features and Treatment OptionsAbstractBullous diseases are uncommon in children; however, as they have the potential to affect quality of life, occasionally have long-term side effects in the setting of scarring processes, and carry a rare risk of underlying malignancy [e.g., with paraneoplastic pemphigus (PNP)], knowledge of their clinical presentation and treatment options is essential. Given the rarity of these conditions, our current state of...
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Q2 Results, Biotech Market Weakness Weigh on Stocks of Genomic Tools, MDx Firms in August,Published on Sep 03, 2019Dutch Startup Epify Raises €500,000 in Seed FundingPublished on Sep 25, 2019Nextera DNA Flex Library Preparation for Soil Shotgun Metagenomics AnalysisThis application note from Illumina shows how to explore the taxonomic and functional diversity of soil microbial communities with a comprehensive shotgun metagenomics sequencing workflow.Download it from GenomeWeb's White Paper Channel.
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Q&A: BARDA Director Rick Bright Discusses New Programs, Focus on DiagnosticsPublished on Sep 30, 2019 Carcinoma of Unknown Primary Investigators Pursue Molecular Targets to Tailor TreatmentsPublished on Sep 30, 2019 At HUPO 2019 Proteomics Looks to Solidify Its Place in Broader Research WorldPublished on Sep 27, 2019 UCLA Team Using Electrochemical Liquid Biopsy for Placental Testing Under New NIH GrantPublished on Sep 27, 2019The 'Dark Matter' of Cancer Genomics: Revealing Undetected Structural...
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Pigment Cell & Melanoma ResearchAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.ORIGINAL ARTICLESDelineating the Role of MITF Isoforms in Pigmentation and Tissue HomeostasisJessica L. Flesher, Elyse K. Paterson‐Coleman, Priya Vasudeva, Rolando Ruiz‐Vega, Michaela Marshall, Eric Pearlman, Grant R. MacGregor, Jonathan Neumann, Anand K. GanesanFirst Published: 28 September 2019ORIGINAL ARTICLESKeratinocyte...
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Otolaryngology–Head and Neck Surgery- Volume: 161, Number: 4 (October 2019)HighlightsHighlights from the Current Issue: October 2019John H. KrouseInvited ArticleUnderstanding the Minimal Clinically Important Difference (MCID) of Patient-Reported Outcome MeasuresAhmad R. SedaghatReview ArticlesSystematic Review of Validated Quality of Life and Swallow Outcomes after Transoral Robotic SurgeryAlexa Castellano and Arun SharmaComplications and Outcomes of Chimeric Free Flaps: A Systematic ReviewAbhinav...
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Associations Between Opioid Prescribing Patterns and Overdose Among Privately Insured Adolescents,Cornelius B. Groenewald, Chuan Zhou, Tonya M. Palermo and William C. Van ClevePediatrics PerspectiveUnintentional Symptom Intensification by DoctorsNeil L. Schechter and Samuel Nurko
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Health Dos & Don'ts of Buying Usedman shopping in thrift store1 / 16What's the Big Deal?You might save some money upfront, but buying used can come with hidden costs. From bed bugs to product recalls, things can go sideways sometimes. That doesn't mean you shouldn't buy anything secondhand. But when you get that thrift store itch, know what to watch out for and which things you should never buy used.Swipe to advancetricycle close up2 / 16Do: Be Careful With Kids' StuffWhen it comes to toys and...
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Spider and Varicose Veins Slideshow: Causes, Before-and-After Treatment ImagesSpider Veins on Woman's Legs by Pool1 / 19Spider Veins and Varicose VeinsSpider veins and varicose veins are practically a rite of passage. As we age, many of us find the jagged purple lines or swollen bluish cords spreading across our thighs and calves. These warped blood vessels occur in up to 60% of adults. Find out exactly what they are, what causes them, and how to make them disappear -- and see undoctored before-and-after...
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