ScienceDirect Publication: European Annals of Otorhinolaryngology, Head and Neck DiseasesGuidelines of clinical practice for the management of swallowing disorders and recent dysphonia in the contexte of the COVID-19 pandemicPublication date: Available online 20 April 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Mattei, B Amy de la Bretèque, S. Crestani, L. Crevier-Buchman, C. Galant, S. Hans, A. Julien-Laferrière, A. Lagier, C. Lobryeau, F. Marmouset,...
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BMJ QIR Current IssueImproving patient safety during intrahospital transportation of mechanically ventilated patients with critical illnessAimIntrahospital transportation (IHT) of patients under mechanical ventilation (MV) significantly increases the risk of patient harm. A structured process performed by a well-prepared team with adequate communication among team members plays a vital role in enhancing patient safety during transportation. Design and implementationWe conducted this quality improvement...
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Liposarcoma of oral cavity: Systematic review of cases reported to date and analysis of prognostic factors: AbstractThe aim of this study was to integrate the available data published on Liposarcomas (LPSs) of the oral cavity into an analysis of its clinical features, treatment modalities, and prognostic factors. An electronic search was undertaken in January 2019. The eligibility criteria included publications that had enough clinical and histological information to confirm the diagnosis. Forty‐five...
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Intravascular large B‐cell lymphoma presenting as a nondescript macular eruption:
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Dietary habits in Japanese patients with chronic spontaneous urticaria: AbstractBackgroundChronic spontaneous urticaria (CSU) is defined as the spontaneously appearing weals and/or angioedema for more than 6 weeks. Dietary habits can modulate the pathogenesis of CSU. However, dietary intakes of nutrients or food in CSU patients, compared with healthy controls, have not been examined in quality and quantity.MethodsWe evaluated dietary habits in adult Japanese patients with chronic spontaneous urticaria...
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Autoimmune progesterone dermatitis presenting as recurrent, marked angioedema‐like lip changes: An unusual presentation of an uncommon problem: AbstractAutoimmune progesterone dermatitis is a rare condition with varying clinical presentations. We present a case of autoimmune progesterone dermatitis presenting as recurrent, marked angioedema‐like lip swelling without any other skin changes.
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BMC Research Notes - Latest ArticlesPatient satisfaction and quality of life in breast reconstruction: assessment of outcomes of immediate, delayed, and nonreconstructionThis study was conducted aiming to assess the quality of life and satisfaction of women who had mastectomy treated with and without breast reconstruction.BMC Research Notes - Latest Articles16hLighter serum copper isotopic composition in patients with early non-alcoholic fatty liver diseaseThe occurrence of non-alcoholic fatty liver...
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Antibiotics, Vol. 9, Pages 193: Management of a Case of Peritonitis Due to Neisseria gonorrhoeae Infection Following Pelvic Inflammatory Disease (PID): Antibiotics, Vol. 9, Pages 193: Management of a Case of Peritonitis Due to Neisseria gonorrhoeae Infection Following Pelvic Inflammatory Disease (PID)Antibiotics doi: 10.3390/antibiotics9040193Authors: Maria A. De Francesco Paola Stefanelli Anna Carannante Silvia Corbellini Cinzia Giagulli Giovanni Lorenzin Maurizio Ronconi ...
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Latest Results for Canadian Journal of Anesthesia/Journal canadien d'anesthésiePractical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patientsAbstract A global health emergency has been declared by the World Health Organization as the 2019-nCoV outbreak spreads across the world, with confirmed patients in Canada. Patients infected with 2019-nCoV are at risk for developing respiratory failure and requiring admission to critical care units. While...
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Dry eye induced by exposure to cigarette smoke pollution: An <em>in vivo</em> and <em>in vitro</em> study: Publication date: Available online 19 April 2020Source: Free Radical Biology and MedicineAuthor(s): Juan Li, Shen Nian, Yi Shao, Guangwei Zhang, Rongbin Liang, Lihua Huang, Ali Luo
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Therapeutic potential of ciclesonide inahalation for COVID-19 pneumonia: Report of three cases: Publication date: Available online 16 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Keisuke Iwabuchi, Koichiro Yoshie, Yuichi Kurakami, Kota Takahashi, Yoshio Kato, Tsuneo MorishimaΣικλεσονίδηΜοιραστείτε Ευρετήριο ΑναφορέςΔραστική ουσία - Γενικές πληροφορίεςΓενικάΧορήγησηΠροφυλάξειςΦαρμακολογίαΔιάθεσηΟνομασίεςΕλληνικάΣικλεσονίδηΕλληνικάΚικλεσονίδηΑγγλικάCiclesonideΣύντομη περιγραφήΗ...
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The effect of Tegaderm™ versus EyeGard® on eyelid erythema during general anesthesia: a randomized-controlled trial: AbstractPurposeApplication of adhesive tape to the eyelids during general anesthesia decreases the risk of corneal abrasion but may increase the risk of eyelid injury. The aim of this study was to determine if there is a difference in eyelid erythema when covering the eyelid with either Tegaderm™ or an EyeGard®.MethodsWe conducted a prospective, randomized, double-blind, split-face...
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CancersCancers, Vol. 12, Pages 1005: Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast CancerCancers, Vol. 12, Pages 1005: Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast Cancer Cancers doi: 10.3390/cancers12041005 Authors: Giulia Brisotto Eva Biscontin Elisabetta Rossi Michela Bulfoni Aigars Piruska Simon Spazzapan Cristina Poggiana Riccardo Vidotto Agostino Steffan Alfonso Colombatti Wilhelm T. S. Huck Daniela Cesselli Rita Zamarchi Matteo Turetta...
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Latest Results for Archives of ToxicologyToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adductsAbstract Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant...
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BMJ Open Current IssueEcological study of the association between mental illness with human development, income inequalities and unemployment across OECD countriesObjectivesRecent studies have demonstrated worsened mental health in relatively highly developed countries impacted by social inequalities and unemployment. Here, we investigate (1) whether mental health issues are differently or similarly affected by these social factors and (2) whether their effects on mental health are related or unrelated...
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Epstein–Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact: AbstractBackgroundThe etiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is confirmed. However, the role of other oncoviruses in OPSCC is unknown. Materials and methodsA total of 158 consecutive OPSCC patients treated with curative intent were included. DNA extracted from tumor sections was used to detect Epstein–Barr virus (EBV), HPV,...
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Urogenital Abnormalities in Adenosine Deaminase Deficiency: AbstractBackgroundImproved survival in ADA-SCID patients is revealing new aspects of the systemic disorder. Although increasing numbers of reports describe the systemic manifestations of adenosine deaminase deficiency, currently there are no studies in the literature evaluating genital development and pubertal progress in these patients.MethodsWe collected retrospective data on urogenital system and pubertal development of 86 ADA-SCID patients...
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BMJ Case Reports Last 6 IssuesGuillain-Barre syndrome and posterior reversible leukoencephalopathy syndrome: a rare associationA 69-year-old woman presented with headaches and visual disturbance in the context of marked hypertension secondary to non-compliance with antihypertensive medications. She developed seizures and hyperreflexia, and MRI brain showed changes consistent with posterior reversible encephalopathy syndrome (PRES). She was treated with antihypertensives with the resolution of symptoms....
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Fraser Syndrome: A Stumbling Block for the Anaesthesiologist: disorders.eyes.arizona.eduFraser syndrome is a rare genetic disorder characterized by partial webbing of the fingers and/or toes (partial syndactyly), kidney (renal) abnormalities, genital malformations, and/or, in some cases, complete fusion of the eyelids (cryptophthalmos) that may be associated with malformation of the eyes, causing ...Fraser Syndrome - NORD (National Organization for Rare ...AbstractFraser syndrome is a rare autosomal...
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Labyrinthine Fistula-Our Experience at a Tertiary Hospital: AbstractThis study has aimed to determine the anatomical site of labyrinthine fistula in patients of chronic suppurative otitis media at our centre. Labyrinthine fistulae (LF) are caused by abnormal communications between the inner ear and surrounding structures resulting in perilymph leakage and hearing loss. Labyrinthine fistula represents as erosive loss of the enchondral bone overlying the semicircular canals without loss of perilymph....
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Facial trauma aggravating paediatric orbital cellulitis: We describe a case of paediatric orbital cellulitis with subperiosteal abscess following blunt facial trauma. Clinical features of orbital cellulitis developed on day 1 post-trauma. A subperiosteal collection subsequently formed lateral to the globe, causing significant ocular compromise. Surgical drainage and sinus washout were performed via external incisions, with satisfactory outcome. This case highlights how trauma may represent a non-sinogenic...
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Guillain-Barre syndrome and posterior reversible leukoencephalopathy syndrome: a rare association: A 69-year-old woman presented with headaches and visual disturbance in the context of marked hypertension secondary to non-compliance with antihypertensive medications. She developed seizures and hyperreflexia, and MRI brain showed changes consistent with posterior reversible encephalopathy syndrome (PRES). She was treated with antihypertensives with the resolution of symptoms. Over the following week,...
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Postgraduate Medical Journal Online FirstCOVID-19 pandemic in India: challenges and silver liningsIndia faces multiple major challenges on the COVID-19 front. It is densely populated: 464 people/km2 compared with Italy's 206, Spain's 91, Iran's 52 and the USA's 36. It has a huge population: 1380 million (USA 330 million, Iran 83 million, Italy 60 million, Spain 46 million). Social distancing without total shutdowns is unthinkable, especially in the big cities with crowded streets, trains, buses...
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Hypothermia induced by quetiapine: An 89-year-old woman was brought to the emergency department, responding only to pain (GCS 6), with a rectal temperature of 28.5°C, hypotension (68/40), bradycardia (35/min) and bradypnoea. The remainder of the examination was unremarkable.She was living at home with her son and a caretaker, confined to bed/wheelchair with a history of Alzheimer's dementia, falls, hypothyroidism (on replacement), hypertension and chronic atrial fibrillation (AF) (on amlodipine 5...
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Immune Profile of the Nasal Mucosa in Patients with Cutaneous Leishmaniasis [Fungal and Parasitic Infections]: Localized skin lesions are characteristic of cutaneous leishmaniasis (CL); however, Leishmania (Viannia) species, which are responsible for most CL cases in the Americas, can spread systemically, sometimes resulting in mucosal disease. Detection of Leishmania has been documented in healthy mucosal tissues (conjunctiva, tonsils, and nasal mucosa) and healthy skin of CL patients and in individuals...
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Mesalamine-induced eosinophilic pleural effusion: A 45-year-old woman with a medical history of ulcerative colitis (UC) presented with difficulty in breathing. The patient was diagnosed with UC a month prior to presentation and was started on mesalamine suppository. Chest x-ray (CXR) on presentation showed bilateral pleural effusion, which was confirmed on CT angiogram of the chest. Diagnostic and therapeutic thoracentesis was performed and 0.7 L of pleural fluid was removed from the left side. The...
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Endoscopy-assisted removal of angle foreign body presenting as persistent localised corneal oedema: A 20-year-old man presented to us with injury to the left eye by a glass bulb 3 weeks ago. The acute injury resolved with a peculiar residual localised corneal oedema in the inferior one-third of the cornea . This localised oedema in absence of any evidence of a localised visible injury to the cornea indicated towards a possible retained foreign body. The foreign body visibility was equivocal on gonioscopy....
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Latest ResultsClinical characteristics and outcomes of oligosecretory and non-secretory multiple myelomaAbstract Secretion of monoclonal immunoglobulins (MIg) detected in the serum and/or urine is one of the typical features of multiple myeloma (MM). However, some patients secrete MIg in quantities below "measurable" (termed oligosecretory MM) and others have no detectable MIgs by standard serum and urine immunofixation (termed non-secretory MM). In a cohort of 852 consecutive patients with active...
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Propranolol-induced acneiform eruptions: revisiting a rare cutaneous side effect: Propranolol is a frequently prescribed non-selective beta-blocker for the management of hypertension, cardiac arrhythmias, post myocardial infarction, thyrotoxicosis, tremors and migraine prophylaxis.1 Although rare, it may produce dermatological side effects like exacerbation of psoriasis, atopic dermatitis, alopecia and lupus erythematosus reactions.2 Here we describe a case of propranolol-induced acneiform eruption...
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PLOS Pathogens: New ArticlesContribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infectionby So Ri Jung, Thomas M. Ashhurst, Phillip K. West, Barney Viengkhou, Nicholas J. C. King, Iain L. Campbell, Markus J. Hofer Signal transducers and activators of transcription (STAT) 1 is critical for cellular responses to type I interferons (IFN-Is), with the capacity to determine the outcome of viral infection. We previously showed that while wildtype (WT) mice...
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Nucleic Acid Therapeutics - Table of ContentsPharmacodynamic and Pharmacokinetic Properties of Full Phosphorothioate Small Interfering RNAs for Gene Silencing In VivoNucleic Acid Therapeutics, Ahead of Print.Nucleic Acid Therapeutics - Table of ContentsnowMark above section as read Annals of Nuclear MedicineAI approach of cycle-consistent generative adversarial networks to synthesize PET images to train computer-aided diagnosis algorithm for dementiaAbstract Objective An artificial intelligence...
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JBC Papers in PressTargeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism [Molecular Bases of Disease]Glioblastoma multiforme (GBM) is a malignant brain tumor with a poor prognosis resulting from tumor resistance to anticancer therapy and a high recurrence rate. Compelling evidence suggests that this is driven by subpopulations of cancer stem cells (CSCs) with tumor-initiating potential. ATP-binding cassette...
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Cancer Research Online First ArticlesTumor cell-derived Angiopoietin-2 promotes metastasis in melanomaThe Angiopoietin (Angpt)-TIE signaling pathway controls vascular maturation and maintains the quiescent phenotype of resting vasculature. The contextual agonistic and antagonistic Tie2 ligand ANGPT2 is believed to be exclusively produced by endothelial cells, disrupting constitutive ANGPT1-TIE2 signaling to destabilize the microvasculature during pathological disorders like inflammation and cancer....
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Hindawi Publishing CorporationLimb Ischemic Postconditioning Alleviates Postcardiac Arrest Syndrome through the Inhibition of Mitochondrial Permeability Transition Pore Opening in a Porcine ModelObjective. Previously, the opening of mitochondrial permeability transition pore (mPTP) was confirmed to play a key role in the pathophysiology of postcardiac arrest syndrome (PCAS). Recently, we demonstrated that limb ischemic postconditioning (LIpostC) alleviated cardiac and cerebral injuries after cardiac...
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Hindawi Publishing CorporationVariable Load Demand Scheme for Hybrid AC/DC NanogridThis paper addresses the use of nanogrid technology in resolving the issue of blanket load shedding for domestic consumers. This is accomplished by using different load management techniques and load classification and utilizing maximum solar energy. The inclusion of DC-based load in basic load and DC inverter load in regular load and scheduling of the burst load during the hours of maximum solar PV generation bring...
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Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer: Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods. Plasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC, ), type 2 diabetes (T2DM, ), or diabetic foot ulcer (DFU, ). The intravenous glucose tolerance test (IVGTT) and biochemical...
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Paediatric Posttraumatic Cyst-Like Lesions: A Report of Two Cases and Review of the Literature: Posttraumatic cyst-like lesions are a rare finding after greenstick fractures in children. These asymptomatic, cystic lesions become radiologically apparent 2-4 months after the initial trauma. Conventional radiographs typically show nonexpansile, well-circumscribed lesions in the cortex, proximal to the fracture site. It is important to recognize them as benign to prevent unnecessary concern and additional...
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The Bethesda System for Reporting Thyroid Cytopathology: A Cytohistological Study: Introduction. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is a significant step to standardize the reporting of thyroid fine needle aspiration (FNA). It has high predictive value, reproducibility, and improved clinical significance. Aim. The study was aimed to evaluate the diagnostic utility and reproducibility of "TBSRTC" at our institute. Methods and Material. The study included 646 thyroid FNAs...
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Latest ResultsDerivation of synthetic fuel from waste plastic: investigation of engine operating characteristics on DI diesel engineAbstract The utilization of plastic in day to day life is ever-increasing and has generated a large amount of plastic garbage that needs proper disposal to save the environment from harmful pollution. The plastic waste management becomes a pressing concern in the present scenario in developing countries like India. This research article evaluates the potential of synthetic...
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Efficacy of 0.5% Levofloxacin and 5.0% Povidone-Iodine Eyedrops in Reducing Conjunctival Bacterial Flora: Metagenomic Analysis: Bacteria associated with postoperative endophthalmitis mostly originate from the normal bacterial flora of the patient's conjunctiva and eyelids, so the incidence of endophthalmitis may be reduced by eliminating the ocular and adnexal flora before surgery. We assessed the effectiveness of eyedrops of 0.5% levofloxacin and 5.0% povidone-iodine (PVI) in reducing conjunctival...
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Latest ResultsEcological risk evaluation and source apportionment of heavy metals in park playgrounds: a case study in Xi'an, Shaanxi Province, a northwest city of ChinaAbstract Park playgrounds recently are suffering serious heavy metals contamination in China. It is urgent to assess the ecological risk and identify the sources for heavy metals. A total of 111 topsoil samples were collected from four park playgrounds in Xi'an, and the X-ray fluorescence (XRF) instrument was used to measure the...
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Latest ResultsElectrical resistivity imaging for detection of hydrogeological active zones in karst areas to identify the site of mining waste disposalAbstract Hydrogeological active zones found in mine waste (tailings) dumping sites are a major source of concern that threatens the safety of the environment and groundwater, especially in karstic areas. Therefore, detecting and identifying these regions correctly will help in selecting the appropriate sites for tailings disposal and avoid consequential...
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Cardiac toxicity of acrolein exposure in embryonic zebrafish ( Danio rerio ): AbstractAcrolein is a widely distributed pollutant produced from various sources such as industrial waste, organic combustion, and power plant emissions. It is also intentionally released into irrigation canals to control invasive aquatic plants. Zebrafish (Danio rerio) has a good reputation for being an attractive model organism for developmental and toxicological research. In this study, zebrafish embryos were exposed...
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Latest Results for Oral and Maxillofacial SurgeryRetropharyngeal internal carotid artery: a review of three casesAbstract Introduction The internal carotid artery (ICA) can take multiple pathways as it extends from the carotid bifurcation to the skull base. An aberration of its normal pathway may place the ICA in a retropharyngeal position in close proximity to the posterior pharyngeal wall. Radiographic classification is based on its proximity to the pharynx and/or pathway. We present a series...
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Role of Molecular Chaperones in Carcinogenesis: Mechanism, Diagnosis, and Treatment: The role of molecular chaperones in carcinogenesis is a central theme of many current research efforts worldwide. It is pertinent to clarify that while various chaperones are Hsps, many are not, and vice versa not all Hsps are chaperones. An example of the latter is Hsp32, better known as heme oxygenase-1 (HO-1), which is dealt with in one of the articles in this Special Issue because of its probable involvement...
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Novel Approaches for Diagnosing and Management of Cardiovascular Disorders Mediated by Oxidative Stress: The cardiovascular disease is one of the major healthcare problems of the world population, and understanding its determinants is essential for designing effective interventions.Reactive oxygen species (ROS) are toxic, highly reactive, and unstable compounds formed during a variety of physiological and pathological biochemical reactions. ROS are produced in all viable cells, and strong evidence...
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Ocular Findings in the 16p11.2 Microdeletion Syndrome: A Case Report and Literature Review: The recurrent 16p11.2 microdeletion is characterized by developmental delays and a wide spectrum of congenital anomalies. It has been well reported that individuals with this ∼593-kb interstitial deletion have an increased susceptibility toward the autism spectrum disorder (ASD). Abnormalities of the eye and ocular adnexa are also commonly associated findings seen in individuals with the 16p11.2 microdeletion...
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Retropharyngeal internal carotid artery: a review of three cases: AbstractIntroductionThe internal carotid artery (ICA) can take multiple pathways as it extends from the carotid bifurcation to the skull base. An aberration of its normal pathway may place the ICA in a retropharyngeal position in close proximity to the posterior pharyngeal wall. Radiographic classification is based on its proximity to the pharynx and/or pathway.We present a series of three cases of retropharyngeal ICAs, our goal is...
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Obesity ReviewsBody Composition Measurements from Birth through 5 Years: Challenges, Gaps, and Existing & Emerging Technologies—A National Institutes of Health workshopSummary Body composition estimates are widely used in clinical research and field studies as measures of energy‐nutrient balance, functionality and health. Despite their broad relevance and multiple applications, important gaps remain in techniques available for accurately and precisely quantifying body composition in infants...
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Lipoteichoic acid of Enterococcus faecalis interferes with Porphyromonas gingivalis lipopolysaccharide signaling via IRAK‐M upregulation in human periodontal ligament cells: AbstractPeriodontitis is a chronic inflammatory disease of the gums caused by infection with multispecies oral bacteria. Since the periodontopathic bacteria Porphyromonas gingivalis together with Enterococcus faecalis are frequently detected in patients with a severe form of periodontitis, interactions between their virulence...
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