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Δευτέρα 4 Ιανουαρίου 2016

One-Pot Peptide and Protein Conjugation: Combination of Enzymatic Transamidation and Click Chemistry

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Chem. Commun., 2015, Accepted Manuscript
DOI: 10.1039/C5CC09163B, Communication
Natalie M Rachel, Joelle Pelletier
Enzymatic transamidation and the copper-catalyzed azide-alkyne cycloaddition (CuAAC) were combined to yield covalently conjugated peptides and proteins. Addition of glutathione preserved enzymatic activity in the presence of copper. Tuning the...
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