CORRELATION BETWEEN BMI AND ARTERIAL STIFFNESS IN MIDDLE AGED SUBJECTS

2016-04-04T04-18-37Z
Source: International Journal of Current Research and Review
Niruba R., T. Kannan Kumar, Subha K. C., Vijiyalakshmi.
Background: World wide prevalence of obesity has reached a pandemic proportion. Obesity and Arterial wall stiffness are independent predictors of cardiovascular diseases. We aimed to investigate how BMI affects arterial stiffness. Noninvasive method of measuring arterial stiffness can be applied to assess the elasticity of the vessel wall and reduce the cardiovascular morbidity. Study Design: Cross sectional observational study. Materials and Methods: Subjects n= 50 males, Age group 35-45 years. All participants had a sedentary life style, blood pressure and glycemic status were within normal limits. Subjects with history of peripheral vascular disease, smokers and any other illness that affects arterial compliance were excluded . Arterial stiffness was assessed from Augmentation index (AI) and stiffness index (SI). AI and SI was measured using IR1 model digital finger tip photo pulse plethysmograph. Results: Mean age = 38±2 years, Mean BMI = 26± 3, Mean Stiffness index = 7.4 ±1.4 m/s, Mean Augmentation index= 48 ±2.8 %.Pearson correlation was applied .BMI correlated positively with both augmentation index and stiffness index with r value is +0.437 and + 0.564 respectively. Conclusion: In our study both large and small artery stiffness were assessed. There was increase in arterial wall stiffness with increase in BMI. We conclude obesity affects arterial compliance, which might be the consequences of metabolic regulation, inflammatory pathways and other mechanisms


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