Use of the World Health Organization Quality of Life assessment short version in mild to moderate Parkinson’s disease

Publication date: Available online 23 June 2016
Source:Archives of Physical Medicine and Rehabilitation
Author(s): Sarah K. Hendred, Erin R. Foster
ObjectiveTo investigate the distribution, internal consistency reliability, and convergent and discriminant validity of the World Health Organization QOL assessment short version (WHOQOL-BREF) in persons with mild to moderate PD.DesignCross-sectional.SettingMovement disorders center.ParticipantsConvenience sample of people with PD (n = 96) recruited from a movement disorders center and controls (n = 60) recruited from the community.InterventionsNot applicable.Main Outcome MeasureWHOQOL-BREF.ResultsThe WHOQOL-BREF domain data were relatively normally distributed and internal consistency reliability was acceptable (α = 0.65-0.85). PD participants reported lower QOL than controls in all except the Environment domain, and Physical QOL was the most impaired domain in the PD group. Age, fatigue and physical activity limitations predicted Physical QOL; depression, fatigue and apathy predicted Psychological QOL; education, executive dysfunction and apathy predicted Social QOL; and age, education, depression and apathy predicted Environment QOL.ConclusionThe WHOQOL-BREF is a suitable tool to assess QOL in mild to moderate PD. It is relatively normally distributed, internally consistent, effectively discriminates between individuals with and without PD, and correlates with relevant demographic characteristics, PD-related impairments and activity limitations.



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