[Vestibular disorders and nausea during head and neck intensity-modulated radiation therapy].

[Vestibular disorders and nausea during head and neck intensity-modulated radiation therapy].

Cancer Radiother. 2016 Jun 15;

Authors: Berta É, Righini CA, Chamorey E, Villa J, Atallah I, Reyt É, Coffre A, Schmerber S

Abstract
PURPOSE: We studied whether there is a relationship between nausea and vestibular disorders in patients treated with intensity modulated radiation therapy (IMRT) for head and neck cancer.
PATIENTS AND METHODS: We performed a prospective single-centre study that enrolled 31 patients. A videonystagmography was carried out before and within 15 days after radiation therapy for each patient. Nausea was assessed at baseline, every week, and at the post-radiotherapy videonystagmography visit.
RESULTS: Twenty-six patients had benefited from a complete interpretable videonystagmography. For 14 of these patients vestibular damage was diagnosed post-radiotherapy. During irradiation, six patients felt nauseous, but without dizziness. In univariate analysis, we found a relationship statistically significant between the average dose received by the vestibules and vestibular disorder videonystagmography (P=0.001, odds ratio [OR]: 1.08 [1.025-.138]), but there was no relationship between vestibular disorder videonystagmography and nausea (P=0.701).
CONCLUSIONS: Irradiation of the vestibular system during IMRT does not seem to explain the nausea.

PMID: 27318553 [PubMed - as supplied by publisher]

from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/28IyG1K
via IFTTT