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Παρασκευή 28 Οκτωβρίου 2016

Label/quencher-free detection of single-nucleotide changes in DNA using isothermal amplification and G-quadruplexes

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Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01600F, Communication
Il Joon Lee, Nam-In Goo, Dong-Eun Kim
We report a analytical method that exploits the interaction between G-quadruplexes and thioflavin T (ThT), for detecting mutant DNA species containing single-base changes. This system is a label/quencher-free fluorescent enhancement...
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