ACOX2 deficiency in primary malignant cardiac tumors [Biological Sciences]

ACOX2 (acyl-CoA oxidase 2) is a peroxisomal enzyme that plays a key role in the metabolism of bile acid intermediates and the oxidation of branched-chain fatty acids. A recent PNAS paper by Vilarinho et al. (1) on ACOX2 deficiency in an 8-y-old male with elevated transaminase levels identifies a homozygous...

http://ift.tt/2p1JNM8