Phenotypic and molecular evaluation of echinocandin susceptibility of Candida glabrata, Candida bracarensis and Candida nivariensis strains isolated during 30 years in Argentina. [PublishAheadOfPrint]

The echinocandin susceptibility of 122 C. glabrata complex strains (including 5 C. nivariensis and 3 C. bracarensis) were evaluated by microdilution and compared with a molecular tool able to detect FKS mutations. No echinocandin resistance was detected. PCR results coincide with MIC data in 99.25% of the cases (1 C. glabrata was misidentified as resistant) but were 20 hours faster. C. nivariensis FKSs were sequenced showing differences with C. glabrata FKSs.

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