 | Related Articles |
Central Nervous System Prophylaxis for Aggressive B-cell Lymphoma: Who, What, and When?
Hematol Oncol Clin North Am. 2016 Dec;30(6):1277-1291
Authors: Schmitz N, Nickelsen M, Savage KJ
Abstract
Central nervous system (CNS) relapse of aggressive B-cell lymphoma is a rare but serious complication with poor survival. Different approaches have been used to define risks factors for CNS relapse and establish prophylactic measures. Although patients with low or intermediate risk of CNS relapse should not undergo special diagnostic or therapeutic measures, CNS MRI as well as cytology and flow cytometry of the cerebrospinal fluid are suggested for high-risk patients (and patients with testicular involvement) at diagnosis, and prophylactic high-dose methotrexate in patients without proven CNS involvement. Future risk and treatment models may include molecular features and new treatment options.
PMID: 27888881 [PubMed - indexed for MEDLINE]
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/2gynBEN
via IFTTT
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου