Cytotoxic-mediated spontaneous regression of eruptive tufted angioma in a teenage girl

Abstract

Tufted angioma (TA) is a rare vascular lesion commonly occurring in infancy and early childhood. Presentation is usually a solitary violaceous macule or patch, frequently on the head, neck and upper trunk. It slowly progresses to a deep, indurated, often painful, red to purple plaque, with superimposed papules/nodules, then it stabilizes. Multiple and/or eruptive variants have been occasionally described. Its course varies, including persistence, complication with Kasabach-Merrit syndrome and complete or partial spontaneous regression.

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