Publication date: Available online 5 July 2017
Source:American Journal of Otolaryngology
Author(s): Samuel J. Trosman, Rohith Bhargavan, Brandon L. Prendes, Brian B. Burkey, Joseph Scharpf
PurposeTo determine the accuracy of intraoperative frozen section analysis on thyroidectomy specimens stratified by the Bethesda classification scheme and its utility for intraoperative decision-making.Study designRetrospective chart review.MethodsA retrospective review was performed on all patients who underwent thyroidectomy or thyroid lobectomy with intraoperative frozen sections at a tertiary care academic center from 2009 to 2015.ResultsThere were 74 total patients who underwent partial or total thyroidectomy with intraoperative frozen section analysis of a thyroid nodule whom had previously undergone a thyroid fine needle aspiration of the nodule. The sensitivity, specificity, positive predictive value, and negative predictive value for a thyroid frozen section with respect to its prediction for malignancy was 81%, 95%, 98%, and 66%, respectively, with a diagnostic accuracy of 85%. For 37 patients with an indeterminate cytologic diagnosis on fine needle aspiration (Bethesda categories III–V), the sensitivity, specificity, positive predictive value, and negative predictive value for a thyroid frozen section was 81%, 91%, 95%, and 67%, respectively, with a diagnostic accuracy of 84%. False positives and false negatives resulted in 1 completion thyroidectomy for benign pathology and 3 reoperations for malignancy not discovered on frozen section.ConclusionWhile intraoperative frozen sections on thyroid specimens may be helpful if positive, the false negative rate remains high. There appears to be limited value in routine frozen sections to guide clinical management and decision-making in the era of the Bethesda system.
http://ift.tt/2tT31tx
Αρχειοθήκη ιστολογίου
-
►
2020
(289)
- ► Φεβρουαρίου (28)
-
►
2019
(9071)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3642)
- ► Ιανουαρίου (3200)
-
►
2018
(39872)
- ► Δεκεμβρίου (3318)
- ► Σεπτεμβρίου (3683)
- ► Φεβρουαρίου (2693)
- ► Ιανουαρίου (3198)
-
▼
2017
(41099)
- ► Δεκεμβρίου (3127)
- ► Σεπτεμβρίου (2173)
-
▼
Ιουλίου
(4578)
-
▼
Ιουλ 05
(206)
- Four key challenges to the design of blended learn...
- The Distribution of Two-Phase R32 Over an Impactin...
- A hairy port-wine stain with overlying hyperhidros...
- Expression of monoacylglycerol lipase as a marker ...
- Tumescent local anaesthesia for early dermatosurge...
- A potential contribution of psoriasin to vascular ...
- Depression and Suicidality in Psoriasis: Review of...
- Association of atopy and tentative diagnosis of sk...
- Infatile hemangiomas with minimal or arrested grow...
- Noonan syndrome with multiple lentigines with PTPN...
- Amenamevir, a novel helicase–primase inhibitor, fo...
- Alopecia developed in a transitional case from pem...
- Teachers and their implementation of differentiate...
- Spiny keratoderma: case series and review
- Leprosy: an enigmatic disease
- Antineoplastic therapy-associated flagellate derma...
- Adolescent girl with frizzy hair knotted in a bundle
- Role of oxidative stress in melasma: a prospective...
- Safety and pharmacodynamics of intranasal GSK22450...
- Histopathological investigation of intranodular ec...
- Metastatic squamous cell carcinoma to the superior...
- The contemporary utility of intraoperative frozen ...
- Japanese standard for clinical stabilometry assess...
- Japanese standard for clinical stabilometry assess...
- The contemporary utility of intraoperative frozen ...
- Metastatic squamous cell carcinoma to the superior...
- Histopathological investigation of intranodular ec...
- Anesthesia for Intestinal Transplantation
- Anesthesia for Heart Transplantation
- Transplantation Anesthesia: The Role of the Anesth...
- Anesthetic Considerations in Transplant Recipients...
- Anesthesia and Perioperative Care in Reconstructiv...
- Anesthesia for Lung Transplantation
- Anesthesia Management of Organ Donors
- Infectious Complications and Malignancies Arising ...
- Response to Letter to the Editor: Prevalence of ve...
- Editorial Board
- Letter to the Editor, regarding the article: "Prev...
- Letter to the editor regarding ‘Evaluation of vita...
- Reconstruction of parotidectomy and lateral skull ...
- Hearing health access in developing countries.
- Reconstruction of parotidectomy and lateral skull ...
- Hearing health access in developing countries.
- Breakthrough attacks in patients with hereditary a...
- Echocardiographic Assessment of Mitral Stenosis Or...
- Tranexamic Acid Does Not Influence Cardioprotectio...
- Reporting of Perioperative Adverse Events by Pedia...
- The US Opioid Crisis: A Role for Enhanced Recovery...
- Prophylactic Norepinephrine Infusion for Preventin...
- Methodological and Reporting Quality of Systematic...
- Patients Undergoing Orthotopic Liver Transplantati...
- Anesthesia Adverse Events Voluntarily Reported in ...
- Identifying novel genes and biological processes r...
- Issue Information
- Computational fluid dynamics and the study of sino...
- Determinants of Incident Metabolic Syndrome in a M...
- Nonblanching, Palpable Skin Lesions With a Linear ...
- Diversity in the Selection of Dermatology Applicants
- Diversity in the Selection of Dermatology Applicants
- Nivolumab for Treatment-Related Vitiligo in Relaps...
- Diversity in the Selection of Dermatology Applicants
- Perineural Invasion of Cutaneous Squamous Cell Car...
- Topical Steroids in Chinese Cosmetics
- Geographic Reasoning on Multi-Modal Fire Spread Data
- Expression of Hormone Receptors and HER-2 in Benig...
- Expression of Hormone Receptors and HER-2 in Benig...
- Vertaling van een essay van Yoko Tawada "Accent"
- Mechanisms of action, resistance and toxicity of i...
- Psychosocial factors and physiological responsivit...
- Uptake and metabolism of sulphated steroids by the...
- Pulse, polarization and topology shaping of polari...
- Proteomic analysis of the neutrophil cytoskeleton,...
- Predictors and correlates of relational aggression...
- Methylome analysis of extreme chemoresponsive pati...
- Practice and outcomes for radical urological cance...
- Portosystemic shunts in cirrhosis are associated t...
- Positron impact ionization phenomena
- A Four-Biomarker Blood Signature Discriminates Sys...
- Associations between tobacco control mass media ca...
- Optimizing Nutrition in Preterm Low Birth Weight I...
- Quantification of within-sample genetic heterogene...
- Adaptive Deep Brain Stimulation for Movement Disor...
- PEI-mediated transient gene expression in cell cul...
- Comparison of subjective sleep and fatigue in brea...
- Exploring the potential role of the advanced nurse...
- Study of Efficacy and Safety of NIR178 and PDR001 ...
- Improving Evidence-Based Care for Cancer Patients
- De improviserende planner : inspiratie voor nieuwe...
- Powerful New Technique Can Clone Thousands of Gene...
- ‘Se lieie la favola’: Apuleian Play in Basile’s 'L...
- Een onwaarschijnlijk verhaal: de Latijnse sprookje...
- HgSe/CdE (E = S, Se) Core/Shell Nanocrystals by Co...
- In het spoor van Vergilius
- E-health beyond technology: analyzing the paradigm...
- A Monk’s Tale: Framing the Fictional in John of Al...
- Een zwerver komt thuis – telkens opnieuw: de klass...
- Non-destructive monitoring of delamination healing...
- Nieuwe grondhouding in ruimtelijk beleid : pleidoo...
- The appropriated city : citizens taking control?
- Real-time emotion classification of tweets
-
▼
Ιουλ 05
(206)
-
►
2016
(13807)
- ► Δεκεμβρίου (700)
- ► Σεπτεμβρίου (600)
- ► Φεβρουαρίου (1350)
- ► Ιανουαρίου (1400)
-
►
2015
(1500)
- ► Δεκεμβρίου (1450)
Ετικέτες
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου