Αρχειοθήκη ιστολογίου

Δευτέρα 7 Αυγούστου 2017

Living Kidney Donor Phenotype and Likelihood of Postdonation Follow-up.

Background: The Organ Procurement and Transplantation Network requires that United States transplant centers maintain follow-up with living donors for 2 years postdonation, but lack of donor follow-up is pervasive. Donor characteristics, including younger age, minority race, and lower education, have been associated with incomplete follow-up, but it is unknown whether altruistic donors, having no prior connection to their recipient, differ from traditional donors in their likelihood of follow-up. Methods: Utilizing Scientific Registry of Transplant Recipients data, we examined all adult living kidney donors from 2005-2015 (n=63 592) classified as altruistic or traditional, and compared likelihood of 6-month medical follow-up using modified Poisson regression. Results: Altruistic donors did not differ from traditional donors in likelihood of follow-up (aRR: 1.02, 95% CI: 0.99-1.06). Among previously identified at-risk subgroups, however, altruistic donors were more likely to have follow-up than their traditional counterparts, including those who were younger (aRR: 1.04, 95% CI: 1.00-1.09), had less than college education (aRR: 1.05, 95% CI: 1.00-1.11), and were unmarried (aRR: 1.08, 95% CI: 1.04-1.12). Having medical follow-up at 6 months was significantly associated with having follow-up at 1 (aRR: 1.84, 95% CI: 1.75-1.93) and 2 years (aRR: 1.63, 95% CI: 1.56-1.70) postdonation. Conclusions: These data provide additional granularity on living donor phenotypes associated with short-term (6 month) postdonation follow-up, which is important given its association with future likelihood of follow-up. These findings offer the opportunity to tailor and direct educational efforts to increase living donor follow-up, particularly among groups at higher risk of loss to follow-up. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

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