Perioperative use of 5% dextrose to decrease postoperative nausea and vomiting

In a randomized clinical trial comparing the incidence of postoperative nausea and vomiting (PONV) during perioperative administration of 5% dextrose and normal saline in patients undergoing laparoscopic cholecystectomy, Mishra et al. [1] show that perioperative administration of 5% dextrose can reduce PONV significantly and even if PONV occurs, the quantity of rescue antiemetics to combat PONV is also reduced significantly. Many things of this study were well done. The authors used a consistent operation (elective laparoscopic cholecystectomy) and had tried to control most of known factors affecting PONV, such as age, female gender, non-smoking status, Apfel score, durations of anesthesia and operation, intraoperative fluid volumes, etc.

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