Tamoxifen maculopathy in a male patient

DescriptionCase description

A 28-year-old male patient presented with the history of blurring of vision in both the eyes for the past 5 months. The patient was a diagnosed case of desmoid fibromatosis of the right axilla 8 years back. The tumour was initially debulked followed by four cycles of systemic chemotherapy, after which patient was symptom-free for 3 years. The patient noticed an increment in the tumour size, for which he consulted another oncologist. A repeat biopsy was done, which proved the same findings. The patient was started on a combination of tamoxifen 80 mg/day and celecoxib 200 mg/day. He had received tamoxifen at a cumulative dose of 116 g over 4 years. Examination in our clinic revealed visual acuity of 20/20 in both eyes with unremarkable anterior chamber findings. Intraocular pressure was 14 and 16 mm Hg in right and left eye, respectively. Fundus showed bilateral crystalline refractile deposits in the macula, rest of the retinal and optic disc...

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