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Δευτέρα 30 Οκτωβρίου 2017

Dual-target Cancer Theranostic for Glutathione S-Transferase and Hypoxia-inducible Factor-1[small alpha] Inhibition

Chem. Commun., 2017, Accepted Manuscript
DOI: 10.1039/C7CC08162F, Communication
Zan Li, Jie Ding, Chunxia Chen, Jiaying Chang, Binghuan Huang, Zhirong Geng, Zhilin Wang
We developed a dual-target theranostic F671, which could exhibit synergetic anticancer effects for inhibiting the activities of glutathione S-transferase and the accumulation of hypoxia inducible factor-1[small alpha]. F671 undergoes self-immolative cleavage...
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