Front Cover: Quinuclidine and DABCO Enhance the Radiofluorination of 5-Substituted 2-Halopyridines (Eur. J. Org. Chem. /2017)

The Front Cover shows the beneficial effects of added quinuclidine and DABCO, among other bases, on the radiochemical yields of 5-substituted [¹⁸F]2-fluoropyridines from the rapid reactions of short-lived cyclotron-produced [¹⁸F]fluoride ions (t_1/2 = 109.8 min) with 5-substituted 2-halopyridines. These effects can be exploited to facilitate the development of new ¹⁸F-labeled tracers for biomedical imaging with positron emission tomography. More information can be found in the Full Paper by V. W. Pike et al.

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