The sperm-specific Ca2+ channel CatSper (cation channel of sperm) controls the intracellular Ca2+ concentration and, thereby, the swimming behavior of sperm. Human CatSper is activated by progesterone (1, 2), an oviductal hormone, which stimulates Ca2+ influx and motility responses. By patch-clamp recording from human sperm, Mannowetz et al. (3) studied...
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Τρίτη 16 Ιανουαρίου 2018
Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm [Biological Sciences]
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