The 46 clinical isolates of Candida guilliermondii and Candida famata were re-identified genetically, resulting in 27 C. guilliermondii and 12 Candida fermentati strains. The majority of C. guilliermondii, but no C. fermentati, were isolated from blood cultures. C. fermentati was more sensitive to antifungals, hydrogen peroxide and killing by murine macrophages than C. guilliermondii. The C. guilliermondii isolates were echinocandin susceptible in vitro but resistant to micafungin in a murine model of invasive candidiasis.
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