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Τρίτη 1 Μαΐου 2018

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function [Cell Biology]

Medical castration that interferes with androgen receptor (AR) function is the principal treatment for advanced prostate cancer. However, clinical progression is universal, and tumors with AR-independent resistance mechanisms appear to be increasing in frequency. Consequently, there is an urgent need to develop new treatments targeting molecular pathways enriched in lethal...

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