Molecular characterization of nasal MRSA isolates showing increasing prevalence of mupirocin resistance and associated multi-drug resistance following attempted decolonization. [PublishAheadOfPrint]

Sequential methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients following attempted mupirocin nasal decolonisation showed an increase in mupirocin resistance (MR) from 6.6% to 20%. MR isolates from patients who failed decolonization yielded indistinguishable spa types and carried multiple antimicrobial- and antiseptic-resistance genes, which may guide infection control and prevention.

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