Αρχειοθήκη ιστολογίου

Δευτέρα 30 Ιουλίου 2018

Absence of K13 Polymorphism in Plasmodium falciparum Parasites from Brazilian Endemic Areas. [PublishAheadOfPrint]

P. falciparum ART-resistant parasites can be evaluated examining polymorphisms in the Kelch (PfK13) domain. 69 samples from falciparum malaria patients were analyzed. All samples were from Brazilian endemic areas of the following states: Acre (n=14), Amapá (n=15), Amazonas (n=30) and Pará (n=10). After DNA alignment with the 3D7 reference sequence all samples were found to be wild-type. These data provide a baseline on PfK13 and reinforce the pertinence of ACTs treatment in Brazilian areas.



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