Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing [Medical Sciences]

The precise correction of genetic mutations at the nucleotide level is an attractive permanent therapeutic strategy for human disease. However, despite significant progress, challenges to efficient and accurate genome editing persist. Here, we report a genome editing platform based upon a class of hematopoietic stem cell (HSC)-derived clade F adeno-associated...

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