Underestimation of house dust mite-specific IgE with extract-based ImmunoCAPs compared to molecular ImmunoCAPs

Publication date: Available online 27 July 2018

Source: Journal of Allergy and Clinical Immunology

Author(s): Huey-Jy Huang, Yvonne Resch-Marat, Azahara Rodriguez-Dominguez, Kuan-Wei Chen, Renata Kiss, Petra Zieglmayer, René Zieglmayer, DI, Patrick Lemell, Friedrich Horak, Rudolf Valenta, Susanne Vrtala

Summary

We identified 6 house dust mite (HDM) allergen molecules to comprising the majority of HDM IgE-binding components and show that molecular ImmunoCAPs based on these six allergens are superior to allergen extract-based ImmunoCAPs for quantifying HDM-specific IgE.

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