Vaginal gel component hydroxyethyl cellulose significantly enhances the infectivity of Chlamydia trachomatis serovars D and E [Mechanisms of Action]

The transmission of the urogenital serovars of Chlamydia trachomatis can be significantly influenced by vaginal gels. Hydroxyethyl cellulose is a commonly used gelling agent which can be found in vaginal gels. Hydroxyethyl cellulose showed a concentration dependent growth enhancing effect on Chlamydia trachomatis serovars D and E with a 26.1 fold maximal increase in vitro and a 2.57 fold increase in vivo.

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