Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency

Grieco, G; Janssens, V; Chevronnay, HPG; N'Kuli, F; Van Der Smissen, P; Wang, T; Shan, J; ... Courtoy, PJ; + view all Grieco, G; Janssens, V; Chevronnay, HPG; N'Kuli, F; Van Der Smissen, P; Wang, T; Shan, J; Vainio, S; Bilanges, B; Jouret, F; Vanhaesebroeck, B; Pierreux, CE; Courtoy, PJ; - view fewer (2018) Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency. Scientific Reports , 8 , Article 14133. 10.1038/s41598-018-32389-z . Green open access

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