A rare case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma

Tsutomu Nomura, MD, DDS, PhD; Daisuke Maki, MD; Fumihiko Matsumoto, MD, PhD; Taisuke Mori, DDS, PhD; Seichi Yoshimoto, MD, PhD

Abstract

Lacrimal sac tumors are rare and difficult to diagnose. We present a case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma in a 73-year-old woman who presented with swelling of the inner canthus. Biopsy identified the growth as an adenocarcinoma. After dissection of the lacrimal carcinoma via a lateral rhinotomy, histopathologic examination confirmed the adenocarcinoma and identified a coexisting transitional cell carcinoma. A recurrence developed, but only of the adenocarcinoma component. For the recurrence, the patient was treated with wide resection, including the orbital contents, and subsequent irradiation. At 49 months postoperatively, the patient remained alive but with a lung metastasis. Wide resection was the key to treatment.

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