"Drug Allergy in children and adults: is it the double X chromosome?"

It is well established that autoimmune diseases, atopic conditions and asthma affect adult females more frequently than adult males. This discrepancy typically develops after childhood and affects females differently depending on their life cycle. As children, males have higher total and allergen specific IgE levels than females and are more likely to suffer from atopic disease and asthma than girls. However, as adults, this prevalence reverses and females are more likely to develop atopic conditions such as food allergies, atopic dermatitis, urticaria, angioedema and asthma.

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