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Τρίτη 27 Νοεμβρίου 2018

Metabolic programming a lean phenotype by deregulation of RNA polymerase III [Biochemistry]

As a master negative regulator of RNA polymerase (Pol) III, Maf1 modulates transcription in response to nutrients and stress to balance the production of highly abundant tRNAs, 5S rRNA, and other small noncoding RNAs with cell growth and maintenance. This regulation of Pol III transcription is important for energetic economy...

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