Behavior of melanocytes and keratinocytes in reticulate acropigmentation of Kitamura

Abstract

Reticulate acropigmentation of Kitamura (RAK, OMIM 615537) is a rare genetic pigmentary disorder that usually shows an autosomal dominant pattern of inheritance with high penetrance. The disorder was first described by Kitamura and Akamatsu in 1943, and then reported worldwide in 1953 (Kitamura et al., 1953). RAK patients typically present within the first or second decade of life with angulated and slightly depressed reticulate hyperpigmentation on the dorsum of the extremities without hypopigmented macules.

This article is protected by copyright. All rights reserved.

from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1R3gzWH
via IFTTT