Preoperative glycosylated haemoglobin as a predictor of postoperative analgesic requirements in diabetic patients: A prospective observational study

BACKGROUND: In diabetic individuals undergoing surgery, the analgesic effect of opioids on postoperative pain may be different from normal. Although the ability of glycosylated haemoglobin (HbA1c) to predict adverse events and outcomes after major surgery has recently been assessed, the ability of HbA1c to predict the need for postoperative analgesia has not been determined. OBJECTIVES: The objective of this study is to evaluate the relationship between preoperative glycaemic control in diabetic individuals and the opioid requirement for postoperative pain treatment. DESIGN: A prospective observational study. SETTING: Single university hospital. PATIENTS: Fifty-two diabetic patients undergoing open nephrectomy surgery. MAIN OUTCOME MEASURES: To evaluate the effect of long-term glucose control on postoperative analgesia requirements, the patients were divided into those with good glycaemic control (HbA1c

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