Short-term Improvement in Physical Activity and Body Composition Following Supervised Exercise Training Program in Idiopathic Pulmonary Fibrosis

Publication date: Available online 8 February 2016
Source:Archives of Physical Medicine and Rehabilitation
Author(s): Baruch Vainshelboim, Benjamin Daniel Fox, Mordechai Reuven Kramer, Shimon Izhakian, Evgeni Gershman, Jose Oliveira
ObjectiveTo examine the effect of participating in a 12-week supervised exercise training (ET) program on physical activity and body composition in Idiopathic Pulmonary Fibrosis (IPF) patients.DesignRandomized controlled trial assessing physical activity and body composition at baseline, after 12-weeks intervention and at 11 months follow up.SettingHospital outpatient Pulmonary Institute.ParticipantsThirty four patients with IPF (68±8 yr) recruited for this study, 32 patients completed the 12-week intervention (ET group, n=15, control group, n=17) and 28 patients (14 in each group) reassessed at 11 months follow-up from baseline.InterventionParticipation in a 12-week supervised ET program or regular medical treatment.Main Outcome MeasureChanges in physical activity levels as measured by International Physical Activity Questionnaire.ResultsAfter 12-weeks intervention physical activity levels were significantly enhanced in the ET group while the control group showed a trend of deterioration [median difference between the groups (interquartile range) 2164 (1576) METS-min/week, p<0.001]. Body composition was also significantly improved in the ET group, while the control group showed an opposite trend. At 11 months follow-up no significant differences were observed between the groups in all variables. ET group lost their achieved benefits in the outcomes and returned to near baseline values, while the control group showed a trend toward worsened outcome.ConclusionsPhysical activity and body composition in patients with IPF were improved following 12-week supervised ET program although the benefits were not-sustained at 11 months follow-up. These results may support the efficacy of participating in supervised ET to improve physical activity and body composition in IPF patients, however maintenance strategies are warranted to preserve the enhanced outcomes. Trial registration: NCT01499745, Clinicaltrials.gov



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