Mediastinal osteosarcoma metastasis causing right heart failure due to pulmonary trunk compression

Description

We present the case of a woman aged 27 years with a background of operated femoral osteosarcoma 9 months ago. She was transferred to our hospital with worsening shortness of breath and signs of decompensated heart failure, haemodynamic instability and suspicion of pericardial effusion. Her transthoracic echocardiogram ruled out a pericardial collection but revealed severe tricuspid regurgitation and right ventricular dilation (figure 1A). A chest CT scan demonstrated an anterior mediastinal mass causing pulmonary trunk compression with subsequent right heart strain and bilateral congestive pleural effusions (figure 1B,C). Haemodynamic instability dictated urgent palliative surgical debulking that was performed under local anaesthesia and sedation via an anterior mediastinotomy approach, due to anaesthetic concerns (figure 2A). This resulted in decompression of the pulmonary trunk and improvement in the patient condition to allow further oncological treatment. The subsequent histopathological examination confirmed osteosarcoma metastasis. Following oncological medical...

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