Arlaud et al. (1) raised concerns regarding our small-angle X-ray scattering (SAXS) and EM models of the unbound C1r2s2 tetramer (2). They reference studies supporting an interaction of two C1rs dimers via C1r CCP1–serine protease (SP) interactions. In response, we conducted refinements against our SAXS data by imposing distance restraints...
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Τρίτη 18 Ιουλίου 2017
Reply to Arlaud et al.: Structure of the C1 complex and the unbound C1r2s2 tetramer [Biological Sciences]
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