Effect of a mobile health, sensor-driven asthma management platform on asthma control

Publication date: November 2017
Source:Annals of Allergy, Asthma & Immunology, Volume 119, Issue 5
Author(s): Meredith A. Barrett, Olivier Humblet, Justine E. Marcus, Kelly Henderson, Ted Smith, Nemr Eid, J. Wesley Sublett, Andrew Renda, LaQuandra Nesbitt, David Van Sickle, David Stempel, James L. Sublett
BackgroundAsthma inflicts a significant health and economic burden in the United States. Self-management approaches to monitoring and treatment can be burdensome for patients.ObjectiveTo assess the effect of a digital health management program on asthma outcomes.MethodsResidents of Louisville, Kentucky, with asthma were enrolled in a single-arm pilot study. Participants received electronic inhaler sensors that tracked the time, frequency, and location of short-acting β-agonist (SABA) use. After a 30-day baseline period during which reference medication use was recorded by the sensors, participants received access to a digital health intervention designed to enhance self-management. Changes in outcomes, including mean daily SABA use, symptom-free days, and asthma control status, were compared among the initial 30-day baseline period and all subsequent months of the intervention using mixed-model logistic regressions and χ² tests.ResultsThe mean number of SABA events per participant per day was 0.44 during the control period and 0.27 after the first month of the intervention, a 39% reduction. The percentage of symptom-free days was 77% during the baseline period and 86% after the first month, a 12% improvement. Improvement was observed throughout the study; each intervention month demonstrated significantly lower SABA use and higher symptom-free days than the baseline month (P < .001). Sixty-nine percent had well-controlled asthma during the baseline period, 67% during the first month of the intervention. Each intervention month demonstrated significantly higher percentages than the baseline month (P < .001), except for month 1 (P = .80).ConclusionA digital health asthma management intervention demonstrated significant reductions in SABA use, increased number of symptom-free days, and improvements in asthma control.Trial RegistrationClinicalTrials.gov Identifier: NCT02162576.



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