Home-based program of maintaining unresponsiveness in children with allergic reactions to larger amounts of peanuts

Allergists currently advise most patients with peanut allergy to observe life-long avoidance. This is in contrast to milk and egg allergy, where many children are partly tolerant to the food and tolerance induction with food ladders is routine.1 Twenty-one percent of children with proven peanut allergy at challenges appear to outgrow their clinical reactivity.2 Furthermore, clinical trials using oral, subcutaneous, and epicutaneous peanut immunotherapy have demonstrated that patients vary in the amount of peanut needed to trigger a reaction and that desensitization and to some extent sustained unresponsiveness can be achieved in children and adolescents.

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