Kinetochores are superprotein complexes that orchestrate chromosome segregation via a dynamic interaction with spindle microtubules. A physical connection between CENP-C and the Mis12–Ndc80–Knl1 (KMN) protein network is an important pathway that is used to assemble kinetochores on CENP-A nucleosomes. Multiple outer kinetochore components are phosphorylated by Aurora B kinase to...
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Τρίτη 12 Δεκεμβρίου 2017
Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis [Biochemistry]
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